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   Articles with "exit sites" as a keyword



ER exit sites (ERES) and ER–mitochondria encounter structures (ERMES) often localize proximally

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recommendations! Published in 2022 at "FEBS Letters"

DOI: 10.1002/1873-3468.14497

Abstract: To understand the potential interplay between vesicular trafficking and direct membrane contact sites‐mediated transport, we selected the endoplasmic reticulum (ER), which participates in both modes of inter‐organelle transport. ER–mitochondria encounter structures (ERMES) are direct membrane… read more here.

Keywords: exit sites; structures ermes; sites eres; encounter structures ... See more keywords

Diffusion of Exit Sites on the Endoplasmic Reticulum: A Random Walk on a Shivering Backbone.

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recommendations! Published in 2018 at "Biophysical journal"

DOI: 10.1016/j.bpj.2018.09.007

Abstract: Major parts of the endoplasmic reticulum (ER) in eukaryotic cells are organized as a dynamic network of membrane tubules connected by three-way junctions. On this network, self-assembled membrane domains, called ER exit sites (ERES), provide… read more here.

Keywords: endoplasmic reticulum; shivering backbone; exit sites; walk shivering ... See more keywords
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ER exit sites in Drosophila display abundant ER-Golgi vesicles and pearled tubes but no megacarriers.

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recommendations! Published in 2021 at "Cell reports"

DOI: 10.1016/j.celrep.2021.109707

Abstract: Secretory cargos are collected at endoplasmic reticulum (ER) exit sites (ERES) before transport to the Golgi apparatus. Decades of research have provided many details of the molecular events underlying ER-Golgi exchanges. Essential questions, however, remain… read more here.

Keywords: microscopy; golgi; sites drosophila; exit sites ... See more keywords

Phosphorylation-coupled autoregulation of TANGO1 and Sec16A maintains functional ER exit sites

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recommendations! Published in 2025 at "Nature Communications"

DOI: 10.1038/s41467-025-65409-4

Abstract: Secretory proteins are synthesized in the endoplasmic reticulum (ER) and begin their transport from specialized domains on the ER called ER exit sites (ERES), where COPII proteins assemble. We previously demonstrated that the interaction between… read more here.

Keywords: phosphorylation; tango1 sec16a; exit sites; tango1 ... See more keywords

Anaplasma phagocytophilum effector EgeA facilitates infection by hijacking TANGO1 and SCFD1 from ER–Golgi exit sites to pathogen-occupied inclusions

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recommendations! Published in 2024 at "Proceedings of the National Academy of Sciences of the United States of America"

DOI: 10.1073/pnas.2405209121

Abstract: Significance Anaplasma phagocytophilum, which lives in eukaryotic cells, causes human granulocytic anaplasmosis, a potentially severe to fatal disease. Host proteins TANGO1 and SCFD1 allow transport vesicles to accommodate bulky cargos, thereby preventing traffic congestion at… read more here.

Keywords: tango1 scfd1; exit sites; anaplasma phagocytophilum; scfd1 ... See more keywords

Correlation of exit sites of inducible ventricular tachycardia post-ST elevation myocardial infarction on electrophysiology study, with region of infarct.

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recommendations! Published in 2022 at "Internal medicine journal"

DOI: 10.1111/imj.15891

Abstract: BACKGROUND Ventricular arrhythmia (VA) is the most common cause of sudden cardiac death post-ST elevation myocardial infarction (STEMI). Ventricular tachycardia (VT) may be inducible in electrophysiology studies (EPS) early (48 h post-STEMI and read more here.

Keywords: exit sites; scar; correlation; infarct ... See more keywords

Sec16 and Sed4 interdependently function as interaction and localization partners at ER exit sites

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recommendations! Published in 2023 at "Journal of Cell Science"

DOI: 10.1242/jcs.261094

Abstract: ABSTRACT COPII proteins assemble at ER exit sites (ERES) to form transport carriers. The initiation of COPII assembly in the yeast Saccharomyces cerevisiae is triggered by the ER membrane protein Sec12. Sec16, which plays a… read more here.

Keywords: interaction; localization; sec16 sed4; sed4 ... See more keywords

On the nature of the plant ER exit sites

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recommendations! Published in 2022 at "Frontiers in Plant Science"

DOI: 10.3389/fpls.2022.1010569

Abstract: In plants, the endoplasmic reticulum (ER) and Golgi bodies are not only in close proximity, but are also physically linked. This unique organization raises questions about the nature of the transport vectors carrying cargo between… read more here.

Keywords: cargo; exit sites; golgi cisternae; golgi bodies ... See more keywords