ADSCs‐exo attenuates hepatic ischemia–reperfusion injury after hepatectomy by inhibiting endoplasmic reticulum stress and inflammation
Sign Up to like & getrecommendations! Published in 2023 at "Journal of Cellular Physiology"
DOI: 10.1002/jcp.30968
Abstract: Hepatic ischemia–reperfusion (I/R) injury commonly occurs during liver surgery. Exosomes from adipose‐derived stem cells (ADSCs‐exo) induce a hepatoprotective effect during hepatic I/R injury. This study aimed to investigate the possible mechanism by which ADSCs‐exo attenuates… read more here.
Keywords: reperfusion; exo; adscs exo; injury ... See more keywords
MSC-derived exosomal miR-140-3p improves cognitive dysfunction in sepsis-associated encephalopathy by HMGB1 and S-lactoylglutathione metabolism
Sign Up to like & getrecommendations! Published in 2024 at "Communications Biology"
DOI: 10.1038/s42003-024-06236-z
Abstract: MiRNAs in mesenchymal stem cells (MSCs)-derived exosome (MSCs-exo) play an important role in the treatment of sepsis. We explored the mechanism through which MSCs-exo influences cognitive impairment in sepsis-associated encephalopathy (SAE). Here, we show that… read more here.
Keywords: mscs exo; lactoylglutathione metabolism; exo; mir 140 ... See more keywords
Transition metal catalyzed C-H bond activation by exo-metallacycle intermediates.
Sign Up to like & getrecommendations! Published in 2021 at "Chemical communications"
DOI: 10.1039/d1cc05042g
Abstract: exo-Metallacycles have become the key reaction intermediates in activating various remote C(sp2)-H and C(sp3)-H bonds in the past decade and aided in achieving unusual site-selectivity. Various novel exo-chelating auxiliaries have assisted metals to reach desired… read more here.
Keywords: exo metallacycle; bond activation; exo;
Multiple myeloma patients-derived exosomes as a potential new clinical tool
Sign Up to like & getrecommendations! Published in 2019 at "Annals of Medicine"
DOI: 10.1080/07853890.2018.1561905
Abstract: Introduction: Multiple Myeloma (MM) is a highly heterogeneous neoplasia, usually preceded by a monoclonal-gammopathy-of-undetermined-significance (MGUS). MM has a diverse clinical presentation, variable response to treatment and outcome. Poor response to novel drugs or extramedullary-disease (EMD)… read more here.
Keywords: median exo; response; treatment; disease ... See more keywords
Effects of follicular fluid exosomes on in vitro maturation of porcine oocytes.
Sign Up to like & getrecommendations! Published in 2022 at "Animal biotechnology"
DOI: 10.1080/10495398.2022.2114084
Abstract: Exosomes are related to effective communication between cells. In this study we aimed to investigate the effect of porcine follicular fluid exosomes (FF-Exo) on cumulus expansion, oocyte mitochondrial membrane potential, and maturation in in vitro culture.… read more here.
Keywords: follicular fluid; exo exo; maturation; exo group ... See more keywords
Exosomes transfer miRNAs from cell-to-cell to inhibit autophagy during infection with Crohn’s disease-associated adherent-invasive E. coli
Sign Up to like & getrecommendations! Published in 2020 at "Gut Microbes"
DOI: 10.1080/19490976.2020.1771985
Abstract: ABSTRACT Adherent-invasive E. coli (AIEC), which abnormally colonize the intestinal mucosa of Crohn’s disease (CD) patients, are able to adhere to and invade intestinal epithelial cells (IECs), survive and replicate within macrophages and induce a… read more here.
Keywords: adherent invasive; infection; exo lf82; coli ... See more keywords
Exosome-mediated targeted delivery of NOX4 siRNA ameliorates angiotensin II-induced atrial fibrillation in mice
Sign Up to like & getrecommendations! Published in 2023 at "Europace"
DOI: 10.1093/europace/euad122.578
Abstract: Abstract Funding Acknowledgements Type of funding sources: Public grant(s) – National budget only. Main funding source(s): National Research Foundation of Korea Background Exosomes have gained attention as nanocarrier; however, the poor targeting ability after systemic… read more here.
Keywords: nox4 sirna; atrial fibrillation; exo; ctp exo ... See more keywords
Exosomes containing miR-148a-3p derived from mesenchymal stem cells suppress epithelial-mesenchymal transition in lens epithelial cells
Sign Up to like & getrecommendations! Published in 2025 at "Stem Cells Translational Medicine"
DOI: 10.1093/stcltm/szae091
Abstract: Abstract Epithelial-mesenchymal transition (EMT) of lens epithelial cells (LECs) is responsible for the development of fibrotic cataracts, which contribute to severe visual impairment. Recent evidence has shown that mesenchymal stem cell-derived exosomes (MSC-Exo) can attenuate… read more here.
Keywords: mir 148a; exo; lecs emt; hucmsc exo ... See more keywords
Exosomal miR-93-5p from cancer-associated fibroblasts confers malignant phenotypes on bladder cancer cells by targeting PAFAH1B1
Sign Up to like & getrecommendations! Published in 2022 at "Anti-Cancer Drugs"
DOI: 10.1097/cad.0000000000001453
Abstract: Background Dysregulation of cancer-associated fibroblasts (CAFs) still greatly challenges the treatments for bladder cancer (BC), where exosomal miRNAs derived from CAFs are one of the essential effectors for tumor progression. miR-93-5p is reported to be… read more here.
Keywords: cell; pafah1b1; exo; cancer associated ... See more keywords
A self-assembled nano micelle-exosome with high selectivity and penetrability achieves precise intracartilage lipid delivery
Sign Up to like & getrecommendations! Published in 2025 at "Science Advances"
DOI: 10.1126/sciadv.adv8999
Abstract: To address the challenge of extremely low drug bioavailability in osteoarthritis (OA) cartilage, we developed a self-assembled micelle-exosome system (Mic-Exo) tailored to the specific characteristics of OA cartilage. The hydrophobic lipid layer of Mic-Exo enables… read more here.
Keywords: high selectivity; mic exo; exo; self assembled ... See more keywords
Kidney Stem Cell Reprogramming Drives Spontaneous Hypertension via Exosomes
Sign Up to like & getrecommendations! Published in 2024 at "Physiology"
DOI: 10.1152/physiol.2024.39.s1.723
Abstract: The spontaneously hypertensive rat (SHR) is a commonly used animal model for studying primary hypertension. However, the precise mechanism of these rats developing hypertension remains to be defined. Here, we have first demonstrated that kidney… read more here.
Keywords: shr; physiology; stem cell; exo ... See more keywords