Exocyst Complex Member EXOC5 Is Required for Survival of Hair Cells and Spiral Ganglion Neurons and Maintenance of Hearing
Sign Up to like & getrecommendations! Published in 2017 at "Molecular Neurobiology"
DOI: 10.1007/s12035-017-0857-z
Abstract: The exocyst, an octameric protein complex consisting of Exoc1 through Exoc8, was first determined to regulate exocytosis by targeting vesicles to the plasma membrane in yeast to mice. In addition to this fundamental role, the… read more here.
Keywords: hair cells; hair; mice; spiral ganglion ... See more keywords
Endosidin2-14 Targets the Exocyst Complex in Plants and Fungal Pathogens to Inhibit Exocytosis1[OPEN]
Sign Up to like & getrecommendations! Published in 2019 at "Plant Physiology"
DOI: 10.1104/pp.18.01457
Abstract: Endosidin2-14 shows potential as a small molecule chemical inhibitor as it targets EXO70, a subunit of the exocyst complex, resulting in inhibition of exocytosis in plants and fungal pathogens. The evolutionarily conserved octameric exocyst complex… read more here.
Keywords: endosidin2; plants fungal; fungal pathogens; plant ... See more keywords
The exocyst complex and Rab5 are required for abscission by localizing ESCRT III subunits to the cytokinetic bridge
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Cell Science"
DOI: 10.1242/jcs.226001
Abstract: ABSTRACT Cytokinesis is the final step of cell division following chromosome segregation that generates two daughter cells. The conserved exocyst complex is required for scission of the intercellular cytokinetic bridge, although the molecular mechanisms it… read more here.
Keywords: escrt iii; rab5; cytokinetic bridge; exocyst complex ... See more keywords
EXOC6 (Exocyst Complex Component 6) Is Associated with the Risk of Type 2 Diabetes and Pancreatic β-Cell Dysfunction
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DOI: 10.3390/biology11030388
Abstract: Simple Summary EXOC6 and EXOC6B (EXOC6/6B) are components of the exocyst complex involved in the secretory granule docking. The exact role of EXOC6/6B in pancreatic β-cell function and risk of type 2 diabetes (T2D) required… read more here.
Keywords: exoc6; pancreatic cell; risk; exocyst complex ... See more keywords
Essential Roles of Exocyst Complex Component 3-like 2 on Cardiovascular Development in Mice
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DOI: 10.3390/life12111730
Abstract: Angiogenesis is a process to generate new blood vessels from pre-existing vessels and to maintain vessels, and plays critical roles in normal development and disease. However, the molecular mechanisms underlying angiogenesis are not fully understood.… read more here.
Keywords: development; complex component; development mice; mice ... See more keywords