Articles with "exoenzyme" as a keyword



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Structure-activity relationships for inhibitors of Pseudomonas aeruginosa exoenzyme S ADP-ribosyltransferase activity.

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Published in 2018 at "European journal of medicinal chemistry"

DOI: 10.1016/j.ejmech.2017.11.036

Abstract: During infection, the Gram-negative opportunistic pathogen Pseudomonas aeruginosa employs its type III secretion system to translocate the toxin exoenzyme S (ExoS) into the eukaryotic host cell cytoplasm. ExoS is an essential in vivo virulence factor that… read more here.

Keywords: exoenzyme; pseudomonas aeruginosa; activity relationships; structure activity ... See more keywords