Hindlimb unloading causes regional loading-dependent changes in osteocyte inflammatory cytokines that are modulated by exogenous irisin treatment.
Sign Up to like & getrecommendations! Published in 2020 at "NPJ microgravity"
DOI: 10.1038/s41526-020-00118-4
Abstract: Disuse-induced bone loss is characterized by alterations in bone turnover. Accruing evidence suggests that osteocytes respond to inflammation and express and/or release pro-inflammatory cytokines; however, it remains largely unknown whether osteocyte inflammatory proteins are influenced… read more here.
Keywords: hindlimb; osteocyte inflammatory; exogenous irisin; inflammatory cytokines ... See more keywords
Impact of Sustained Exogenous Irisin Myokine Administration on Muscle and Myocyte Integrity in Sprague Dawley Rats
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DOI: 10.3390/metabo12100939
Abstract: Irisin is an exercise-induced myokine implicated as a fundamental mediator of physical activity benefits. The aim of the present study was to investigate the role of the chronic administration model of irisin on the physiological… read more here.
Keywords: sprague dawley; irisin; dawley rats; muscle ... See more keywords