Systematic evaluation of differential splicing tools for RNA-seq studies
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DOI: 10.1093/bib/bbz126
Abstract: Abstract Differential splicing (DS) is a post-transcriptional biological process with critical, wide-ranging effects on a plethora of cellular activities and disease processes. To date, a number of computational approaches have been developed to identify and… read more here.
Keywords: event based; differential splicing; rna seq; systematic evaluation ... See more keywords
Exon-based Phylogenomics and the Relationships of African Cichlid Fishes: Tackling the Challenges of Reconstructing Phylogenies with Repeated Rapid Radiations
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DOI: 10.1093/sysbio/syac051
Abstract: Abstract African cichlids (subfamily: Pseudocrenilabrinae) are among the most diverse vertebrates, and their propensity for repeated rapid radiation has made them a celebrated model system in evolutionary research. Nonetheless, despite numerous studies, phylogenetic uncertainty persists,… read more here.
Keywords: relationships african; african cichlid; phylogenomics relationships; exon based ... See more keywords
Exploring differential exon usage via short- and long-read RNA sequencing strategies
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DOI: 10.1098/rsob.220206
Abstract: Alternative splicing produces various mRNAs, and thereby various protein products, from one gene, impacting a wide range of cellular activities. However, accurate reconstruction and quantification of full-length transcripts using short-reads is limited, due to their… read more here.
Keywords: short reads; exon usage; rna; exon based ... See more keywords