Position-dependent correlation between TBX22 exon 5 methylation and palatal shelf fusion in the development of cleft palate.
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DOI: 10.1590/0001-3765201920180945
Abstract: DNA methylation is essential for spatiotemporally-regulated gene expression in embryonic development. TBX22 (Chr X: 107667964-107688978) functioning as a transcriptional repressor affects DNA binding, sumoylation, and transcriptional repression associated with X-linked cleft palate. This study aimed… read more here.
Keywords: methylation; cleft palate; palatal shelf; tbx22 exon ... See more keywords