Longitudinal analysis of serum interleukinâ18 in patients with familial Mediterranean fever carrying MEFV mutations in exon 10
Sign Up to like & getrecommendations! Published in 2018 at "Cytokine"
DOI: 10.1016/j.cyto.2017.10.007
Abstract: Background: Familial Mediterranean fever (FMF) is an autoinflammatory disease caused by mutations in the MEFV gene. Mutations in exon 10 are associated with typical FMF phenotypes, and patients with exon 10 mutations have higher serum… read more here.
Keywords: mutations exon; familial mediterranean; exon mutations; serum ... See more keywords
Coexistence of MET exon 14 mutations with EGFR mutations in non-small cell lung cancer.
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Clinical Oncology"
DOI: 10.1200/jco.2017.35.15_suppl.e20636
Abstract: e20636Background: Activation of MET oncogene as the result of amplification or activation MET exon 14 mutations represents an emerging molecular target for non-small cell lung cancer (NSCLC) treatm... read more here.
Keywords: exon mutations; lung cancer; cell lung; non small ... See more keywords
The Amelioration of Myelofibrosis with Thrombocytopenia by a JAK1/2 Inhibitor, Ruxolitinib, in a Post-polycythemia Vera Myelofibrosis Patient with a JAK2 Exon 12 Mutation
Sign Up to like & getrecommendations! Published in 2017 at "Internal Medicine"
DOI: 10.2169/internalmedicine.56.7871
Abstract: Less than 5% of patients with polycythemia vera (PV) show JAK2 exon 12 mutations. Although PV patients with JAK2 exon 12 mutations are known to develop post-PV myelofibrosis (MF) as well as PV with JAK2V617F,… read more here.
Keywords: jak1 inhibitor; polycythemia vera; exon mutations; myelofibrosis ... See more keywords
Prognostic Value of KRAS Exon-specific Mutations in Patients With Colorectal Cancer
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DOI: 10.21873/anticanres.16306
Abstract: Background/Aim: The clinical significance of many RAS-family mutations in colorectal cancer (CRC) remains unclear. The purpose of this study was to investigate the relationship of RAS mutations on an exon basis (i.e., mutations in KRAS… read more here.
Keywords: ras mutations; exon mutations; colorectal cancer; kras exon ... See more keywords
Therapeutic Cancer Vaccination With a Peptide Derived From the Calreticulin Exon 9 Mutations Induces Strong Cellular Immune Responses in Patients With CALR-Mutant Chronic Myeloproliferative Neoplasms
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Oncology"
DOI: 10.3389/fonc.2021.637420
Abstract: Background The calreticulin (CALR) exon 9 mutations that are identified in 20% of patients with Philadelphia chromosome negative chronic myeloproliferative neoplasms (MPN) generate immunogenic antigens. Thus, therapeutic cancer vaccination against mutant CALR could be a… read more here.
Keywords: response; exon mutations; therapeutic cancer; vaccination ... See more keywords