Recurrent evolution of vertebrate transcription factors by transposase capture
Sign Up to like & getrecommendations! Published in 2021 at "Science"
DOI: 10.1126/science.abc6405
Abstract: A recipe for new genes Most lineages contain evolutionarily novel genes, but their origin is not always clear. Cosby et al. investigated the origin of families of lineage-specific vertebrate genes (see the Perspective by Wacholder… read more here.
Keywords: protein; transcription; dna; transposase ... See more keywords
Evidence for exon shuffling is sensitive to model choice.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of bioinformatics and computational biology"
DOI: 10.1142/s0219720021400138
Abstract: The exon shuffling theory posits that intronic recombination creates new domain combinations, facilitating the evolution of novel protein function. This theory predicts that introns will be preferentially situated near domain boundaries. Many studies have sought… read more here.
Keywords: model; evidence exon; exon shuffling; model choice ... See more keywords