Articles with "exon splice" as a keyword



MET Exon 14 Splice-Site Mutations Preferentially Activate KRAS Signaling to Drive Tumourigenesis

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Published in 2022 at "Cancers"

DOI: 10.3390/cancers14061378

Abstract: Simple Summary MET exon 14 splice-site mutations occur in ~3–4% of lung adenocarcinoma cases, defining a cohort of patients which might benefit from anti-MET targeted therapy. Such therapies have yielded mixed results, however, pointing to… read more here.

Keywords: site mutations; exon splice; met ex14; met exon ... See more keywords