Nanopore sequencing of brain-derived full-length circRNAs reveals circRNA-specific exon usage, intron retention and microexons
Sign Up to like & getrecommendations! Published in 2021 at "Nature Communications"
DOI: 10.1038/s41467-021-24975-z
Abstract: Circular RNA (circRNA) is a class of covalently joined non-coding RNAs with functional roles in a wide variety of cellular processes. Their composition shows extensive overlap with exons found in linear mRNAs making it difficult… read more here.
Keywords: retention microexons; intron retention; nanopore sequencing; brain ... See more keywords
Exploring differential exon usage via short- and long-read RNA sequencing strategies
Sign Up to like & getrecommendations! Published in 2022 at "Open Biology"
DOI: 10.1098/rsob.220206
Abstract: Alternative splicing produces various mRNAs, and thereby various protein products, from one gene, impacting a wide range of cellular activities. However, accurate reconstruction and quantification of full-length transcripts using short-reads is limited, due to their… read more here.
Keywords: short reads; exon usage; rna; exon based ... See more keywords
Quantitative RNA-seq meta-analysis of alternative exon usage in C. elegans.
Sign Up to like & getrecommendations! Published in 2017 at "Genome research"
DOI: 10.1101/gr.224626.117
Abstract: Almost 20 years after the completion of the C. elegans genome sequence, gene structure annotation is still an ongoing process with new evidence for gene variants still being regularly uncovered by additional in-depth transcriptome studies.… read more here.
Keywords: gene; rna seq; exon usage;
Analysis of psoriasis‐relevant gene expression and exon usage alterations after silencing of SR‐rich splicing regulators
Sign Up to like & getrecommendations! Published in 2018 at "Experimental Dermatology"
DOI: 10.1111/exd.13530
Abstract: In our recent cDNA microarray experiment, three SR‐rich splicing factors—SFRS18, PPIG and LUC7L3—were shown to exert altered responsiveness upon T‐lymphokine stimulation of psoriatic non‐involved and healthy epidermis samples. We have also demonstrated that double silencing… read more here.
Keywords: gene expression; rich splicing; psoriasis; gene ... See more keywords