Mechanistic decoupling of exonuclease III multifunctionality into AP endonuclease and exonuclease activities at the single-residue level
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DOI: 10.1093/nar/gkac043
Abstract: Abstract Bacterial exonuclease III (ExoIII) is a multifunctional enzyme that uses a single active site to perform two conspicuous activities: (i) apurinic/apyrimidinic (AP)-endonuclease and (ii) 3′→5′ exonuclease activities. The AP endonuclease activity results in AP… read more here.
Keywords: exonuclease activities; exonuclease; endonuclease exonuclease; level ... See more keywords