HEPATIC stellate cell-derived exosomes MODULATE macrophage inflammatory response.
Sign Up to like & getrecommendations! Published in 2021 at "Experimental cell research"
DOI: 10.1016/j.yexcr.2021.112663
Abstract: BACKGROUND Hepatic stellate cell (HSC) differentiation/activation is central to liver fibrosis and is innately linked to the immune response to liver injury. Exosomes (EXOs) are important means of communication between cell populations. This study sought… read more here.
Keywords: hscs; exos; macrophage; culture ... See more keywords
Inhibition of exosomal miR‐24‐3p in diabetes restores angiogenesis and facilitates wound repair via targeting PIK3R3
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Cellular and Molecular Medicine"
DOI: 10.1111/jcmm.15958
Abstract: Diabetic foot ulcer (DFU) is one of the common ailments of elderly people suffering from diabetes. Exosomes containing various active regulators have been found to play a significant role in apoptosis, cell proliferation and other… read more here.
Keywords: exos; mir; inhibition; wound repair ... See more keywords
Hypoxic Tumor-Derived Exosomes Induce M2 Macrophage Polarization via PKM2/AMPK to Promote Lung Cancer Progression
Sign Up to like & getrecommendations! Published in 2022 at "Cell Transplantation"
DOI: 10.1177/09636897221106998
Abstract: Hypoxia is a major regulator of tumor aggressiveness and metastasis in cancer progression. Exosomes (exos) play an important role in the communication between lung cancer and hypoxic microenvironment. However, the underlying mechanisms are largely undefined.… read more here.
Keywords: lung cancer; exos; lung; hypoxia ... See more keywords
Bioprinting of exosomes: Prospects and challenges for clinical applications
Sign Up to like & getrecommendations! Published in 2023 at "International Journal of Bioprinting"
DOI: 10.18063/ijb.690
Abstract: 453Three-dimensional bioprinting (3DBP) is an additive manufacturing technique that has emerged as a promising strategy for the fabrication of scaffolds, which can successfully recapitulate the architectural, biochemical, and physical cues of target tissues. More importantly,… read more here.
Keywords: cell; challenges clinical; exos; exosomes prospects ... See more keywords
M1 macrophage-derived exosome-encapsulated cisplatin can enhance its anti-lung cancer effect.
Sign Up to like & getrecommendations! Published in 2020 at "Minerva medica"
DOI: 10.23736/s0026-4806.20.06564-7
Abstract: BACKGROUND To study the efficacy of cisplatin-loaded M1 macrophage secreted-exosomes (DDP-M1-Exos) in enhancing DDP anti-tumor effect. METHODS M1-Exos were first extracted using density gradient centrifugation, and the DDP-M1-Exos system was established via electroporation. Then, the… read more here.
Keywords: exos; system; lung cancer; tumor ... See more keywords
Exosomes Derived From miR-212-5p Overexpressed Human Synovial Mesenchymal Stem Cells Suppress Chondrocyte Degeneration and Inflammation by Targeting ELF3
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Bioengineering and Biotechnology"
DOI: 10.3389/fbioe.2022.816209
Abstract: Excessive chondrocyte degeneration and inflammation are the pathological features of osteoarthritis (OA), and altered miR-212-5p may contribute to meniscus and cartilage degeneration. Whether exosomes derived from miR-212-5p overexpressed synovial mesenchymal stem cells (SMSC-212-5p-Exos) could be… read more here.
Keywords: elf3; exos; degeneration; degeneration inflammation ... See more keywords
Unraveling the Proteomic Landscape of Intestinal Epithelial Cell-Derived Exosomes in Mice
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Physiology"
DOI: 10.3389/fphys.2022.773671
Abstract: Purpose This study aimed to identify the biological functions of small intestine intestinal epithelial cell derived exosomes (IEC-Exos) and further distinguished the difference proteins in IEC-Exos between ileum and jejunum related to function of the… read more here.
Keywords: iec exos; exos; jejunum; epithelial cell ... See more keywords
Hypoxia Alters the Proteome Profile and Enhances the Angiogenic Potential of Dental Pulp Stem Cell-Derived Exosomes
Sign Up to like & getrecommendations! Published in 2022 at "Biomolecules"
DOI: 10.3390/biom12040575
Abstract: Dental pulp stem cells (DPSCs) and their exosomes (Exos) are effective treatments for regenerative medicine. Hypoxia was confirmed to improve the angiogenic potential of stem cells. However, the angiogenic effect and mechanism of hypoxia-preconditioned DPSC-Exos… read more here.
Keywords: proteome profile; exos; hypo exos; angiogenic potential ... See more keywords