Articles with "exosite modulators" as a keyword



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Novel Approaches and Challenges of Discovery of Exosite Modulators of a Disintegrin and Metalloprotease 10

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Published in 2020 at "Frontiers in Molecular Biosciences"

DOI: 10.3389/fmolb.2020.00075

Abstract: A disintegrin and metaproteinase 10 is an important target for multiple therapeutic areas, however, despite drug discovery efforts by both industry and academia no compounds have reached the clinic so far. The lack of enzyme… read more here.

Keywords: novel approaches; challenges discovery; approaches challenges; discovery exosite ... See more keywords