Tumor-derived exosomal HMGB1 promotes esophageal squamous cell carcinoma progression through inducing PD1+ TAM expansion
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DOI: 10.1038/s41389-019-0126-2
Abstract: Macrophages constitute one of the most common components of immune cells, which penetrate tumors and they have a key role in tumor prognosis. Here, we identified an unrecognized macrophage subpopulation, which favors tumorigenesis. These macrophages… read more here.
Keywords: esophageal squamous; exosomal hmgb1; pd1 tam; cell ... See more keywords
CARDIOPULMONARY BYPASS-DERIVED PLASMA EXOSOMAL HMGB1 CONTRIBUTES TO ALVEOLAR EPITHELIAL CELL NECROPTOSIS VIA mtDNA/CGAS/STING PATHWAY
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DOI: 10.1097/shk.0000000000002006
Abstract: ABSTRACT Our previous study confirmed that cardiopulmonary bypass (CPB) leads to acute lung injury (ALI) via inducing high-mobility group box 1 (HMGB1) release. Recent research showed that HMGB1 promotes pulmonary injury mainly via exosomes transport.… read more here.
Keywords: necroptosis; exosomal hmgb1; mtdna; plasma exosomal ... See more keywords