The role of exosomal miRNA in nonalcoholic fatty liver disease.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of cellular physiology"
DOI: 10.1002/jcp.30699
Abstract: Nonalcoholic fatty liver disease (NAFLD) impacts more than one-third of the population and is linked with other metabolic diseases. The term encompasses a wide spectrum of diseases, from modest steatosis to nonalcoholic steatohepatitis, fibrosis and,… read more here.
Keywords: exosomal mirna; liver disease; role exosomal; fatty liver ... See more keywords
Effects of Chronic PM2.5 Exposure on Pulmonary Epithelium: Transcriptome analysis of mRNA-Exosomal miRNA Interaction.
Sign Up to like & getrecommendations! Published in 2019 at "Toxicology letters"
DOI: 10.1016/j.toxlet.2019.09.010
Abstract: Epidemiological studies have established the correlation between PM2.5 and a wide variety of pulmonary diseases. However, their underlying pathogeneses have not been clearly elucidated yet. In the present study, the epithelial-mesenchymal transition (EMT) phenotype with… read more here.
Keywords: pm2; chronic pm2; exo mirs; exosomal mirna ... See more keywords
Photoelectrochemical Detection of Exosomal miRNAs by Combining Target-Programmed Controllable Signal Quenching Engineering.
Sign Up to like & getrecommendations! Published in 2022 at "Analytical chemistry"
DOI: 10.1021/acs.analchem.1c04086
Abstract: MicroRNAs extracted from exosomes (exosomal miRNAs) have recently emerged as promising biomarkers for early prognosis and diagnosis. Thus, the development of an effective approach for exosomal miRNA monitoring has triggered extensive attention. Herein, a sensitive… read more here.
Keywords: exosomal mirna; detection exosomal; detection; release ... See more keywords
Expression of urinary exosomal miRNA-615-3p and miRNA-3147 in diabetic kidney disease and their association with inflammation and fibrosis
Sign Up to like & getrecommendations! Published in 2023 at "Renal Failure"
DOI: 10.1080/0886022x.2022.2121929
Abstract: Abstract Background Diabetic kidney disease (DKD) is one of the most common chronic complications of type 2 diabetes mellitus (T2DM), and it is particularly important to identify a high-quality method for evaluating disease progression. Urinary… read more here.
Keywords: exosomal mirna; inflammation fibrosis; expression; urinary exosomal ... See more keywords
Cancer-Associated Fibroblast-Derived Exosomal miRNA-320a Promotes Macrophage M2 Polarization In Vitro by Regulating PTEN/PI3Kγ Signaling in Pancreatic Cancer
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Oncology"
DOI: 10.1155/2022/9514697
Abstract: Our previous study has indicated that cancer-associated fibroblasts (CAFs) play a crucial role in regulating gemcitabine resistance through transferring exosomal miRNA-106b to cancer cells. Tumor-associated macrophages (TAMs) are recently verified to facilitate gemcitabine resistance. However,… read more here.
Keywords: macrophage polarization; exosomal mirna; cancer; mirna 320a ... See more keywords
Alteration of Myeloid-Derived Suppressor Cells, Chronic Inflammatory Cytokines, and Exosomal miRNA Contribute to the Peritoneal Immune Disorder of Patients With Endometriosis
Sign Up to like & getrecommendations! Published in 2018 at "Reproductive Sciences"
DOI: 10.1177/1933719118808923
Abstract: Immunologic disorder has been reported to promote the progression of endometriosis (EMT). It has been known that myeloid-derived suppressor cells (MDSCs) drive the progression of many types of diseases. Few studies have shown the relation… read more here.
Keywords: suppressor cells; derived suppressor; mdscs; cytokines exosomal ... See more keywords
Exosomal miRNA signature of pancreatic cyst: Liquid biopsies as indicators of pancreatic cancer.
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Clinical Oncology"
DOI: 10.1200/jco.2018.36.4_suppl.225
Abstract: 225Background: Pancreatic cysts are a group of lesions with malignant potential. Currently, there are no consistently reliable biomarkers or imaging modalities to accurately predict biologic behavior of these cysts. We tested the hypothesis that tumor-derived… read more here.
Keywords: cyst; pancreatic cancer; exosomal mirna; mirna signature ... See more keywords
Exosomal miRNA in early-stage hepatocellular carcinoma
Sign Up to like & getrecommendations! Published in 2023 at "World Journal of Clinical Cases"
DOI: 10.12998/wjcc.v11.i3.528
Abstract: The incidence and mortality of hepatic carcinoma (HCC) remain high, and early diagnosis of HCC is seen as a key approach in improving clinical outcomes. However, the sensitivity and specificity of current early screening methods… read more here.
Keywords: hepatocellular carcinoma; early stage; exosomal mirna; stage hepatocellular ... See more keywords
Comprehensive microRNA-sequencing of exosomes derived from head and neck carcinoma cells in vitro reveals common secretion profiles and potential utility as salivary biomarkers
Sign Up to like & getrecommendations! Published in 2017 at "Oncotarget"
DOI: 10.18632/oncotarget.19614
Abstract: Exosomes are nano-scale, membrane encapsulated vesicles that are released by cells into the extracellular space and function as intercellular signaling vectors through horizontal transfer of biologic molecules, including microRNA (miRNA). There is evidence that cancer-derived… read more here.
Keywords: hnscc cell; secretion; hnscc; exosomal mirna ... See more keywords
Radiotherapy-induced overexpression of exosomal miRNA-378a-3p in cancer cells limits natural killer cells cytotoxicity.
Sign Up to like & getrecommendations! Published in 2020 at "Epigenomics"
DOI: 10.2217/epi-2019-0193
Abstract: Aim: We here hypothesized that tumor-derived exosomal miRNA (TexomiR) released from irradiated tumors may play a role in the tumor cells escape to natural killer (NK) cells. Materials & methods: Our study included the use of… read more here.
Keywords: natural killer; cells cytotoxicity; exosomal mirna; cancer cells ... See more keywords
Prospecting of exosomal-miRNA signatures as prognostic marker for gestational diabetes mellitus and other adverse pregnancy outcomes
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Endocrinology"
DOI: 10.3389/fendo.2023.1097337
Abstract: Exosomal microRNA (ExomiRs) serves as potential cargo molecules responsible for post-translation of gene expression and intracellular communication playing a vital role in acting as clinically relevant prognostic biomarkers for identifying pregnancy-associated complications in patients. ExomiRs… read more here.
Keywords: prospecting exosomal; exosomal mirna; pregnancy outcomes; gestational diabetes ... See more keywords