Emerging roles of exosomal miRNAs in breast cancer drug resistance
Sign Up to like & getrecommendations! Published in 2019 at "IUBMB Life"
DOI: 10.1002/iub.2116
Abstract: Breast cancer (BC), as a heterogeneous disease, is considered as one of the most common malignancies in women worldwide. The resistance of BC cells to therapeutic agents has remained a big challenge in the treatment… read more here.
Keywords: drug resistance; exosomal mirnas; emerging roles; breast cancer ... See more keywords
Exosomal miRNAs in osteoarthritis
Sign Up to like & getrecommendations! Published in 2020 at "Molecular Biology Reports"
DOI: 10.1007/s11033-020-05443-1
Abstract: Exosomes, as lipid nanostructure, are secreted by approximately all cell types within the body and actively involved in either short or long distances cell–cell communication in an autocrine and paracrine manner. Recently, exosomes are widely… read more here.
Keywords: mirnas osteoarthritis; exosomal mirnas; biology;
Exosomal microRNAs as diagnostic and therapeutic biomarkers in non-malignant liver diseases
Sign Up to like & getrecommendations! Published in 2021 at "Archives of Pharmacal Research"
DOI: 10.1007/s12272-021-01338-2
Abstract: The liver is a vital organ responsible for various physiological functions, such as metabolism, immune response, digestion, and detoxification. Crosstalk between hepatocytes, hepatic macrophages, and hepatic stellate cells is critical for liver pathology. Exosomes are… read more here.
Keywords: exosomal mirnas; liver diseases; pathology; liver pathology ... See more keywords
Exosomal MicroRNA-Based Predictive Model for Preclinical Alzheimer’s Disease: A Multicenter Study
Sign Up to like & getrecommendations! Published in 2022 at "Biological psychiatry"
DOI: 10.1016/j.biopsych.2021.12.015
Abstract: BACKGROUND Exosomal microRNAs (miRNAs) have been demonstrated to be biomarkers of Alzheimer's disease (AD). However, whether exosomal miRNAs can predict AD at the asymptomatic stage remains unclear. METHODS This study is a multicenter study with… read more here.
Keywords: study; multicenter study; exosomal mirnas; dataset subjects ... See more keywords
Integrating exosomal microRNAs and electronic health data improved tuberculosis diagnosis
Sign Up to like & getrecommendations! Published in 2019 at "EBioMedicine"
DOI: 10.1016/j.ebiom.2019.01.023
Abstract: Background Tuberculosis (TB) is difficult to diagnose under complex clinical conditions as electronic health records (EHRs) are often inadequate in making an affirmative diagnosis. As exosomal miRNAs emerged as promising biomarkers, we investigated the potential… read more here.
Keywords: exosomal mirnas; diagnosis; mir; electronic health ... See more keywords
Exosomal microRNAs have great potential in the neurorestorative therapy for traumatic brain injury
Sign Up to like & getrecommendations! Published in 2022 at "Experimental Neurology"
DOI: 10.1016/j.expneurol.2022.114026
Abstract: Traumatic brain injury (TBI) is a leading cause of brain impairment, resulting in acute neural impairment and chronic long-term disability worldwide. Until now, no therapeutics developed can improve the neurological recovery and clinical prognosis of… read more here.
Keywords: tbi; therapy; exosomal mirnas; neurorestorative therapy ... See more keywords
Serum exosomal microRNA transcriptome profiling in subacute spinal cord injured rats.
Sign Up to like & getrecommendations! Published in 2019 at "Genomics"
DOI: 10.1016/j.ygeno.2019.12.003
Abstract: MicroRNAs (miRNAs) are involved in a series of pathology of spinal cord injury (SCI). Although, locally expressed miRNAs have advantages in studying the pathological mechanism, they cannot be used as biomarkers. The "free circulation" miRNAs… read more here.
Keywords: exosomal mirnas; exosomal microrna; microrna transcriptome; serum exosomal ... See more keywords
Photoelectrochemical Detection of Exosomal miRNAs by Combining Target-Programmed Controllable Signal Quenching Engineering.
Sign Up to like & getrecommendations! Published in 2022 at "Analytical chemistry"
DOI: 10.1021/acs.analchem.1c04086
Abstract: MicroRNAs extracted from exosomes (exosomal miRNAs) have recently emerged as promising biomarkers for early prognosis and diagnosis. Thus, the development of an effective approach for exosomal miRNA monitoring has triggered extensive attention. Herein, a sensitive… read more here.
Keywords: exosomal mirna; detection exosomal; detection; release ... See more keywords
Piezotronic Effect-Assisted Photoelectrochemical Exosomal MicroRNA Monitoring Based on an Electron Donor Self-Supplying Strategy.
Sign Up to like & getrecommendations! Published in 2022 at "Analytical chemistry"
DOI: 10.1021/acs.analchem.2c02821
Abstract: Exosomal microRNAs (miRNAs) as newly emerging reliable and noninvasive biomarkers have demonstrated a significant function in early cancer diagnosis. Photoelectrochemical (PEC) biosensing has attracted unprecedented attention in exosomal miRNA monitoring due to its inherent advantages… read more here.
Keywords: effect; strategy; monitoring; exosomal mirnas ... See more keywords
Thermophoretic Detection of Exosomal microRNAs by NanoFlares.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of the American Chemical Society"
DOI: 10.1021/jacs.9b13960
Abstract: Exosomal microRNAs (miRNAs) are reliable and non-invasive biomarkers for the early diagnosis of cancer. Yet, accurate and feasible detection of exosomal miRNAs is often hampered by the low abundance of miRNAs in exosomes and the… read more here.
Keywords: thermophoretic detection; exosomal micrornas; detection; exosomal mirnas ... See more keywords
Circulating exosomes and exosomal microRNAs as biomarkers in gastrointestinal cancer
Sign Up to like & getrecommendations! Published in 2017 at "Cancer Gene Therapy"
DOI: 10.1038/cgt.2016.77
Abstract: The most important biological function of exosomes is their possible use as biomarkers in clinical diagnosis. Compared with biomarkers identified in conventional specimens such as serum or urine, exosomal biomarkers provide the highest amount of… read more here.
Keywords: exosomal micrornas; exosomal mirnas; circulating exosomes; biomarkers gastrointestinal ... See more keywords