Infarct Zone: a Novel Platform for Exosome Trade in Cardiac Tissue Regeneration
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Cardiovascular Translational Research"
DOI: 10.1007/s12265-019-09952-8
Abstract: The global incidence of coronary artery diseases (CADs), especially myocardial infarction (MI), has drastically increased in recent years. Even though the conventional therapies have improved the outcomes, the post-MI complications and the increased rate of… read more here.
Keywords: tissue engineering; cardiac tissue; regeneration; tissue ... See more keywords
Molecular characteristics and functional differences of anti-PM/Scl autoantibodies and two other distinct and unique supramolecular structures known as "EXOSOMES".
Sign Up to like & getrecommendations! Published in 2020 at "Autoimmunity reviews"
DOI: 10.1016/j.autrev.2020.102644
Abstract: The term "exosome" has been applied to three distinct supramolecular entities, namely the PM/Scl autoantibodies or "RNA exosomes", transforming DNA fragments termed "DNA exosomes", and small size extracellular vesicles knows as "exosomes". Some of the… read more here.
Keywords: known exosomes; exosome; molecular characteristics; characteristics functional ... See more keywords
A Two-Layered Targeting Mechanism Underlies Nuclear RNA Sorting by the Human Exosome.
Sign Up to like & getrecommendations! Published in 2020 at "Cell reports"
DOI: 10.1016/j.celrep.2020.01.068
Abstract: Degradation of transcripts in human nuclei is primarily facilitated by the RNA exosome. To obtain substrate specificity, the exosome is aided by adaptors; in the nucleoplasm, those adaptors are the nuclear exosome-targeting (NEXT) complex and the… read more here.
Keywords: targeting mechanism; two layered; layered targeting; exosome ... See more keywords
RNA helicases are hubs that orchestrate exosome-dependent 3'-5' decay.
Sign Up to like & getrecommendations! Published in 2020 at "Current opinion in structural biology"
DOI: 10.1016/j.sbi.2020.09.010
Abstract: The RNA exosome is a conserved complex of proteins that mediates 3'-5' RNA processing and decay. Its functions range from processing of non-coding RNAs such as ribosomal RNAs and decay of aberrant transcripts in the… read more here.
Keywords: decay; exosome; rna helicases; dependent decay ... See more keywords
Quantification of Exosome Based on a Copper-Mediated Signal Amplification Strategy.
Sign Up to like & getrecommendations! Published in 2018 at "Analytical chemistry"
DOI: 10.1021/acs.analchem.8b01187
Abstract: Exosomes, a class of small extracellular vesicles, play important roles in various physiological and pathological processes by serving as vehicles for transferring and delivering membrane and cytosolic molecules between cells. Since exosomes widely exist in… read more here.
Keywords: based copper; copper mediated; copper; mediated signal ... See more keywords
Structure of the nuclear exosome captured on a maturing preribosome
Sign Up to like & getrecommendations! Published in 2018 at "Science"
DOI: 10.1126/science.aar5428
Abstract: The RNA exosome captured in action The RNA exosome, a major RNA degradation machine, processes ribosomal RNA (rRNA) precursors and is directly coupled to the protein synthesis machine, the ribosome. Using cryo–electron microscopy, Schuller et… read more here.
Keywords: microscopy; rna exosome; exosome captured; exosome ... See more keywords
Abstract 3742: Exosome-mediated EGR1 transportation controls the radiation-induced abscopal effect in head and neck cancer
Sign Up to like & getrecommendations! Published in 2019 at "Tumor Biology"
DOI: 10.1158/1538-7445.am2019-3742
Abstract: Head and neck cancer (HNC) are one of the vital types of metastatic cancer, and radiotherapy (RT) is the convincing treatment regarding its location. RT can regulate cancer growth in not only directly irradiated cells… read more here.
Keywords: radiation; exosome; cancer; radiation induced ... See more keywords
RNA-binding protein Mub1 and the nuclear RNA exosome act to fine-tune environmental stress response
Sign Up to like & getrecommendations! Published in 2021 at "Life Science Alliance"
DOI: 10.26508/lsa.202101111
Abstract: Comparative RNA interactome capture identifies potential regulators of RNA metabolism in fission yeast and reveals RNA exosome–dependent buffering of stress-responsive gene expression networks. The nuclear RNA exosome plays a key role in controlling the levels… read more here.
Keywords: exosome; rna binding; stress; nuclear rna ... See more keywords