Targeting Tetraspanins at Cell Interfaces: Functional Modulation and Exosome‐Based Drug Delivery for Precise Disease Treatment
Sign Up to like & getrecommendations! Published in 2024 at "ChemMedChem"
DOI: 10.1002/cmdc.202400664
Abstract: Tetraspanins are key players in various physiological and pathological processes, including malignancy, immune response, fertilization, and infectious disease. Affinity ligands targeting the interactions between tetraspanins and partner proteins are promising for modulating downstream signaling pathways,… read more here.
Keywords: cell interfaces; exosome based; drug delivery; delivery ... See more keywords
Exosomes, and the potential for exosome‐based interventions against COVID‐19
Sign Up to like & getrecommendations! Published in 2024 at "Reviews in Medical Virology"
DOI: 10.1002/rmv.2562
Abstract: Since late 2019, the world has been devastated by the coronavirus disease 2019 (COVID‐19) induced by severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2), with more than 760 million people affected and ∼seven million deaths reported.… read more here.
Keywords: potential exosome; exosomes potential; based interventions; exosome based ... See more keywords
Regenerative Skin Remodeling through Exosome-Based Therapy: A Case Study Demonstrating 21-Month Sustained Outcomes in Pore Size, Erythema, and Hyperpigmentation
Sign Up to like & getrecommendations! Published in 2025 at "Dermatology and Therapy"
DOI: 10.1007/s13555-025-01501-3
Abstract: Visible signs of skin aging, including enlarged pores, rosacea, and melasma, are often difficult to treat due to their multifactorial etiology. Most conventional therapies offer only temporary improvement and require ongoing maintenance. Exosome-based treatments present… read more here.
Keywords: therapy; exosome based; pore size; exosome ... See more keywords
HACE2-Exosome-Based Nano-Bait for Concurrent SARS-CoV-2 Trapping and Antioxidant Therapy
Sign Up to like & getrecommendations! Published in 2022 at "ACS Applied Materials & Interfaces"
DOI: 10.1021/acsami.1c19541
Abstract: Corona Virus Disease 2019 (COVID-19) pandemic, caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is seriously threatening human health. Following SARS-CoV-2 infection, immune cell infiltration creates an inflammatory and oxidative microenvironment, which can cause… read more here.
Keywords: sars cov; exosome based; nano bait; pda exosome ... See more keywords
Implication of an exosome-based gene signature for estimating clinical outcomes of triple-negative breast cancer and assisting in individualized therapy
Sign Up to like & getrecommendations! Published in 2025 at "Scientific Reports"
DOI: 10.1038/s41598-025-16751-6
Abstract: Exosomes play a crucial role in triple-negative breast cancer (TNBC), influencing various aspects of tumor progression. Given the importance of exosomes in TNBC biology, we proposed a novel exosome-based model that was critically implicated in… read more here.
Keywords: exosome based; clinical outcomes; based gene; exosome ... See more keywords
Exosome-based delivery nanoplatforms: next-generation theranostic platforms for breast cancer.
Sign Up to like & getrecommendations! Published in 2022 at "Biomaterials science"
DOI: 10.1039/d2bm00062h
Abstract: Breast cancer is the most frequent type of malignancy, and the leading cause of cancer-related death in women across the globe. Exosomes are naturally derived 50-150 nm nanovesicles with a variety of bioactive molecules to… read more here.
Keywords: cancer; based delivery; breast cancer; exosome based ... See more keywords
Utilization of exosome-based therapies to augment anti-PD-1/PD-L1 therapies
Sign Up to like & getrecommendations! Published in 2025 at "Journal for Immunotherapy of Cancer"
DOI: 10.1136/jitc-2024-010603
Abstract: Abstract The development of immune checkpoint inhibitors targeting the programmed cell death 1 (PD-1)/programmed cell death ligand 1 (PD-L1) pathway has significantly transformed the landscape of cancer treatment. However, resistance mechanisms such as alternative immune… read more here.
Keywords: anti therapies; therapies augment; exosome based; based therapies ... See more keywords
Abstract 3064: Exosome-based therapeutic strategy for neuroendocrine prostate cancer
Sign Up to like & getrecommendations! Published in 2023 at "Cancer Research"
DOI: 10.1158/1538-7445.am2023-3064
Abstract: Background: Therapy-induced neuroendocrine prostate cancer (NEPC) is an aggressive variant of castration-resistant prostate cancer (CRPC) that is increasing in incidence with the widespread use of second generation of androgen receptor (AR)-pathway inhibitors (APIs) such as… read more here.
Keywords: exosome based; prostate cancer; cancer; neuroendocrine prostate ... See more keywords
Abstract 832: Exosome-based hybrid nanosystem for targeted TNBC therapy
Sign Up to like & getrecommendations! Published in 2023 at "Cancer Research"
DOI: 10.1158/1538-7445.am2023-832
Abstract: Treatment of metastatic Triple-Negative Breast Cancer (TNBC) remains a challenge despite an increasing number of newer drugs being approved in recent years. The major challenge for improved treatment outcomes for metastatic cancer originates from the… read more here.
Keywords: based hybrid; exosome based; cancer; hybrid nanosystem ... See more keywords
Exosome therapeutics for non-small cell lung cancer tumorigenesis
Sign Up to like & getrecommendations! Published in 2024 at "Cancer Cell International"
DOI: 10.1186/s12935-024-03544-6
Abstract: Non-small cell lung cancer (NSCLC) remains an ongoing health concern, with poor treatment options and prognosis for many patients. Typically, individuals with lung cancer are detected at the middle and terminal stages, resulting in poor… read more here.
Keywords: cancer; non small; therapy; lung cancer ... See more keywords
Exosome-based immunotherapy: a promising approach for cancer treatment
Sign Up to like & getrecommendations! Published in 2020 at "Molecular Cancer"
DOI: 10.1186/s12943-020-01278-3
Abstract: In the era of the rapid development of cancer immunotherapy, there is a high level of interest in the application of cell-released small vesicles that stimulate the immune system. As cell-derived nanovesicles, exosomes show great… read more here.
Keywords: immunotherapy; exosome based; immunotherapy promising; cancer immunotherapy ... See more keywords