The diagnostic and prognostic value of serum exosome‐derived carbamoyl phosphate synthase 1 in HEV‐related acute liver failure patients
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Medical Virology"
DOI: 10.1002/jmv.27961
Abstract: Early diagnosis and prognosis evaluation are of great significance to hepatitis E virus (HEV)‐related acute liver failure (HEV‐ALF) patients. We collected serum samples from 200 health controls (HCs), 200 patients with acute hepatitis E (AHE),… read more here.
Keywords: serum exosome; hev alf; exosome derived; derived cps1 ... See more keywords
Hepatic exosome-derived miR-130a-3p attenuates glucose tolerance via suppressing PHLPP2 gene in adipocyte.
Sign Up to like & getrecommendations! Published in 2019 at "Metabolism: clinical and experimental"
DOI: 10.1016/j.metabol.2019.154006
Abstract: OBJECTIVE Glucose and lipid metabolism disorder is a major risk factor for type II diabetes and cardiovascular diseases. Evidence has indicated that the interplay between the liver and adipose tissue is crucial in maintaining energy… read more here.
Keywords: hepatic exosome; mice; derived mir; mir 130a ... See more keywords
Exosome-derived uterine microRNAs isolated from cows with endometritis impede blastocyst development.
Sign Up to like & getrecommendations! Published in 2019 at "Reproductive biology"
DOI: 10.1016/j.repbio.2019.06.003
Abstract: As a common disease of cows occurring during their perinatal period, endometritis is known to affect fertility. At present, the studies on endometritis mainly focus on preventing microbial invasion. However, the mechanism that uterine inflammation… read more here.
Keywords: derived uterine; cows endometritis; micrornas isolated; blastocyst ... See more keywords
Exosome-derived microRNAs improve cardiac function
Sign Up to like & getrecommendations! Published in 2020 at "Nature Reviews Cardiology"
DOI: 10.1038/s41569-020-00498-w
Abstract: A new study identifies microRNAs that are enriched in exosomes secreted from cardiosphere-derived cells and which are associated with cardiac repair in pigs and humans with dilated cardiomyopathy. read more here.
Keywords: improve cardiac; cardiology; cardiac function; derived micrornas ... See more keywords
Retracted Article: Exosome-derived PTENP1 suppresses cisplatin resistance of bladder cancer (BC) by suppressing cell proliferation, migration and inducing apoptosis via the miR-103a/PDCD4 axis
Sign Up to like & getrecommendations! Published in 2019 at "RSC Advances"
DOI: 10.1039/c9ra07823a
Abstract: Bladder cancer (BC) is a lethal cancer that threatens the health of millions of people. read more here.
Keywords: bladder cancer; retracted article; cancer; article exosome ... See more keywords
Biological functions and molecular mechanisms of exosome-derived circular RNAs and their clinical implications in digestive malignancies: the vintage in the bottle
Sign Up to like & getrecommendations! Published in 2024 at "Annals of Medicine"
DOI: 10.1080/07853890.2024.2420861
Abstract: Abstract Background Circular RNAs (circRNAs) are identified as a novel family of endogenous RNA molecules through ‘back-splicing’ and covalently linked at the 5′ and 3′ ends. Emerging researches have demonstrated circRNAs are stable and abundant… read more here.
Keywords: functions molecular; digestive malignancies; molecular mechanisms; biological functions ... See more keywords
High prevalence of mutant KRAS in circulating exosome-derived DNA from early-stage pancreatic cancer patients
Sign Up to like & getrecommendations! Published in 2017 at "Annals of Oncology"
DOI: 10.1093/annonc/mdx004
Abstract: Background Exosomes arise from viable cancer cells and may reflect a different biology than circulating cell-free DNA (cfDNA) shed from dying tissues. We compare exosome-derived DNA (exoDNA) to cfDNA in liquid biopsies of patients with… read more here.
Keywords: pdac patients; mutant kras; early stage; cancer ... See more keywords
Plasma extracellular nanovesicle (exosome)‐derived biomarkers for drug metabolism pathways: a novel approach to characterize variability in drug exposure
Sign Up to like & getrecommendations! Published in 2019 at "British Journal of Clinical Pharmacology"
DOI: 10.1111/bcp.13793
Abstract: Demonstrate the presence of cytochrome P450 (CYP) and UDP‐glucuronosyltransferase (UGT) proteins and mRNAs in isolated human plasma exosomes and evaluate the capacity for exosome‐derived biomarkers to characterize variability in CYP3A4 activity. read more here.
Keywords: characterize variability; plasma extracellular; drug; derived biomarkers ... See more keywords
Plasma exosome derived MiR221 as a driver of long term hypoxia induced aberrations in pulmonary arterial phenotype in fetal sheep
Sign Up to like & getrecommendations! Published in 2023 at "Physiology"
DOI: 10.1152/physiol.2023.38.s1.5796248
Abstract: Pregnancy at high altitude (> 2500 meters) reduces oxygenation to the fetus (i.e., gestational hypoxia). The low oxygenation causes abnormal fetal lung development, with pulmonary arteries becoming thicker and dysfunctional. Associated with these structural and… read more here.
Keywords: development; hypoxia; physiology; pulmonary arterial ... See more keywords
Exosome-Derived Noncoding RNAs as a Promising Treatment of Bone Regeneration
Sign Up to like & getrecommendations! Published in 2021 at "Stem Cells International"
DOI: 10.1155/2021/6696894
Abstract: The reconstruction of large bone defects remains a crucial challenge in orthopedic surgery. The current treatments including autologous and allogenic bone grafting and bioactive materials have their respective drawbacks. While mesenchymal stem cell (MSC) therapy… read more here.
Keywords: treatment bone; bone regeneration; derived noncoding; bone ... See more keywords
Exosome-Derived microRNA: Potential Target for Diagnosis and Treatment of Sepsis
Sign Up to like & getrecommendations! Published in 2024 at "Journal of Immunology Research"
DOI: 10.1155/2024/4481452
Abstract: Exosome-derived microRNAs (miRNAs) are emerging as pivotal players in the pathophysiology of sepsis, representing a new frontier in both the diagnosis and treatment of this complex condition. Sepsis, a severe systemic response to infection, involves… read more here.
Keywords: diagnosis treatment; exosome derived; sepsis; derived microrna ... See more keywords