Exosome-mediated Bidirectional Signaling between Mesenchymal Stem Cells and Chondrocytes for Enhanced Chondrogenesis
Sign Up to like & getrecommendations! Published in 2019 at "Biotechnology and Bioprocess Engineering"
DOI: 10.1007/s12257-019-0332-y
Abstract: Exosomes of human mesenchymal stem cells (hMSC) are known to effectively increase the proliferation rate of chondrocytes and stimulate cartilage extracellular matrix. However, the therapeutic efficacy of the other signaling direction (i.e., the effect of… read more here.
Keywords: cell populations; stem cells; exosome mediated; mesenchymal stem ... See more keywords
MSC exosomes mediate cartilage repair by enhancing proliferation, attenuating apoptosis and modulating immune reactivity.
Sign Up to like & getrecommendations! Published in 2018 at "Biomaterials"
DOI: 10.1016/j.biomaterials.2017.11.028
Abstract: Mesenchymal stem cell (MSC) exosome was previously shown to be effective in repairing critical size osteochondral defects in an immunocompetent rat model. Here we investigate the cellular processes modulated by MSC exosomes and the mechanism… read more here.
Keywords: cartilage repair; msc exosomes; proliferation; exosome mediated ... See more keywords
Exosome-mediated transfer of circRNA CircNFIX enhances temozolomide resistance in glioma.
Sign Up to like & getrecommendations! Published in 2020 at "Cancer letters"
DOI: 10.1016/j.canlet.2020.03.002
Abstract: Development of chemotherapy resistance remains a major obstacle for glioma management. Exosome-mediated transfer of circular RNAs (circRNAs) are being found to have relevance to many human cancers, including glioma. The purpose of this study is… read more here.
Keywords: mediated transfer; glioma; circnfix; resistance ... See more keywords
Exosome-Mediated Ultra-Effective Direct Conversion of Human Fibroblasts into Neural Progenitor-like Cells.
Sign Up to like & getrecommendations! Published in 2018 at "ACS nano"
DOI: 10.1021/acsnano.7b08297
Abstract: Exosomes, naturally secreted nanoparticles, have been introduced as vehicles for horizontal transfer of genetic material. We induced autologous exosomes containing a cocktail of reprogramming factors ("reprosomes") to convert fibroblasts into neural progenitor cells (NPCs). The… read more here.
Keywords: neural progenitor; mediated ultra; fibroblasts neural; exosome mediated ... See more keywords
Key role of exportin 6 in exosome-mediated viral transmission from insect vectors to plants
Sign Up to like & getrecommendations! Published in 2022 at "Proceedings of the National Academy of Sciences of the United States of America"
DOI: 10.1073/pnas.2207848119
Abstract: Significance Exosomes are a type of membranous extracellular vesicle and have been highlighted for their various roles in the transmission of microorganisms. Exportins are frequently found in exosomes. However, the function of exportins sorted in… read more here.
Keywords: exportin exosome; role exportin; transmission; exosome mediated ... See more keywords
HGG-16. EXOSOME-MEDIATED INTER-CLONAL INTERACTIONS IN PEDIATRIC GBM AND DIPG
Sign Up to like & getrecommendations! Published in 2020 at "Neuro-Oncology"
DOI: 10.1093/neuonc/noaa222.303
Abstract: Abstract Pediatric Glioblastoma (pGBM) and Diffuse Intrinsic Pontine Glioma (DIPG) are highly heterogeneous brain tumors which we demonstrated are comprised by distinct sub-clones interacting in a functional network. Exosomes are known to mediate the crosstalk… read more here.
Keywords: inter clonal; dipg; mediated inter; cell ... See more keywords
Exosome-Mediated miR-21 Was Involved in the Promotion of Structural and Functional Recovery Effect Produced by Electroacupuncture in Sciatic Nerve Injury
Sign Up to like & getrecommendations! Published in 2022 at "Oxidative Medicine and Cellular Longevity"
DOI: 10.1155/2022/7530102
Abstract: Purpose Our study is aimed at investigating the mechanism by which electroacupuncture (EA) promoted nerve regeneration by regulating the release of exosomes and exosome-mediated miRNA-21 (miR-21) transmission. Furthermore, the effects of Schwann cells- (SC-) derived… read more here.
Keywords: sciatic nerve; pni; exosome mediated; mir ... See more keywords
Abstract 35: Triple-negative breast cancer cells alter the pulmonary landscape to favor metastasis via exosome-mediated release of NM23
Sign Up to like & getrecommendations! Published in 2018 at "Cancer Research"
DOI: 10.1158/1538-7445.am2018-35
Abstract: There is strong evidence implicating exosomes, cell-derived nanoscale vesicles, and their protein cargo in facilitating dialogue between primary tumor cells and the premetastatic niche. Identified by our lab as one such protein, secreted nucleoside diphosphate… read more here.
Keywords: negative breast; breast cancer; cancer; exosome mediated ... See more keywords
Abstract 3814: Overcoming multidrug resistance (MDR) in colorectal cancer by modulating exosome-mediated transfer of MDR transporter regulatory machineries
Sign Up to like & getrecommendations! Published in 2019 at "Cancer Research"
DOI: 10.1158/1538-7445.sabcs18-3814
Abstract: Aim: The study aims to investigate the circumvention of multidrug resistance (MDR) in colorectal cancer by modulating exosome-mediated transfer of MDR transporter regulatory machineries from resistant to sensitive cells. Background: Colorectal cancer is a leading… read more here.
Keywords: cancer; mdr; resistance; transfer ... See more keywords
Visualization of exosome-mediated miR-210 transfer from hypoxic tumor cells
Sign Up to like & getrecommendations! Published in 2017 at "Oncotarget"
DOI: 10.18632/oncotarget.14247
Abstract: Cancer cells actively release exosomes carrying specific cellular components, such as proteins, mRNA, and miRNA, to communicate with various cells in the tumor microenvironment. We visualized exosome-mediated transfer of miR-210 from hypoxic breast cancer cells… read more here.
Keywords: transfer; cancer cells; mir 210; exosome mediated ... See more keywords
Exosome mediated phenotypic changes in lung cancer pathophysiology.
Sign Up to like & getrecommendations! Published in 2017 at "Translational cancer research"
DOI: 10.21037/tcr.2017.07.09
Abstract: Exosomes are small extracellular vesicles with a size range of 40–150 nm and a lipid bilayer membrane (1-4). They contain protein and nucleic acids, and mediate local and systemic intercellular communication (1-3). Many cell types… read more here.
Keywords: mediated phenotypic; changes lung; phenotypic changes; lung cancer ... See more keywords