Exosomes in Cancer Nanomedicine and Immunotherapy: Prospects and Challenges.
Sign Up to like & getrecommendations! Published in 2017 at "Trends in biotechnology"
DOI: 10.1016/j.tibtech.2017.03.004
Abstract: Exosomes (versatile, cell-derived nanovesicles naturally endowed with exquisite target-homing specificity and the ability to surmount in vivo biological barriers) hold substantial promise for developing exciting approaches in drug delivery and cancer immunotherapy. Specifically, bioengineered exosomes… read more here.
Keywords: prospects challenges; nanomedicine immunotherapy; cancer nanomedicine; cancer ... See more keywords
Mechanisms associated with biogenesis of exosomes in cancer
Sign Up to like & getrecommendations! Published in 2019 at "Molecular Cancer"
DOI: 10.1186/s12943-019-0963-9
Abstract: Intercellular communication between cellular compartments within the tumor and at distant sites is critical for the development and progression of cancer. Exosomes have emerged as potential regulators of intracellular communication in cancer. Exosomes are nanovesicles… read more here.
Keywords: associated biogenesis; mechanisms associated; biogenesis exosomes; exosomes cancer ... See more keywords
Exosomes in Cancer Radioresistance
Sign Up to like & getrecommendations! Published in 2019 at "Frontiers in Oncology"
DOI: 10.3389/fonc.2019.00869
Abstract: Radiation is a mainstay of cancer therapy. Radioresistance is a significant challenge in the treatment of locally advanced, recurrent and metastatic cancers. The mechanisms of radioresistance are complicated and still not completely understood. Exosomes are… read more here.
Keywords: radiation induced; radioresistance; cancer radioresistance; exosomes cancer ... See more keywords
Exosomes and cancer immunotherapy: A review of recent cancer research
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Oncology"
DOI: 10.3389/fonc.2022.1118101
Abstract: As phospholipid extracellular vesicles (EVs) secreted by various cells, exosomes contain non-coding RNA (ncRNA), mRNA, DNA fragments, lipids, and proteins, which are essential for intercellular communication. Several types of cells can secrete exosomes that contribute… read more here.
Keywords: cancer; immunotherapy review; exosomes cancer; review recent ... See more keywords
Exosomes in Cancer Therapy
Sign Up to like & getrecommendations! Published in 2022 at "Cancers"
DOI: 10.3390/cancers14030500
Abstract: Exosomes or small extracellular vesicles (EVs) are natural nanoparticles and known to play essential roles in intercellular communications, carrying a cargo of a broad variety of lipids, proteins, metabolites, RNAs (mRNA, miRNA, tRNA, long non-coding… read more here.
Keywords: cancer therapy; exosomes cancer;
Exosomes in Cancer Diagnostics
Sign Up to like & getrecommendations! Published in 2017 at "Cancers"
DOI: 10.3390/cancers9010008
Abstract: Exosomes are endosome derived extracellular vesicles of 30–120 nm size ranges. Exosomes have been identified as mediators of cell-to-cell communication by transferring bioactive molecules such as nucleic acids, proteins and lipids into recipient cells. While… read more here.
Keywords: cancer; cancer diagnostics; exosomes cancer;
Engineering Exosomes for Cancer Therapy
Sign Up to like & getrecommendations! Published in 2017 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms18061122
Abstract: There remains an urgent need for novel therapeutic strategies to treat metastatic cancer, which results in over 8 million deaths annually worldwide. Following secretion, exosomes are naturally taken up by cells, and capable of the… read more here.
Keywords: cancer; engineering exosomes; cancer therapy; exosomes cancer ... See more keywords