Mesenchymal stem cell exosomes promote immunosuppression of regulatory T cells in asthma
Sign Up to like & getrecommendations! Published in 2018 at "Experimental Cell Research"
DOI: 10.1016/j.yexcr.2017.12.021
Abstract: Abstract Mesenchymal stem cells (MSCs) and regulatory T cells (Tregs) are both potent immune‐modulators. The aberrant proliferation and function of Tregs plays an important role in the development of asthma. Our previous studies have demonstrated… read more here.
Keywords: exosomes promote; regulatory cells; msc exosomes; proliferation ... See more keywords
Macrophage-Derived Exosomes Promote Bone Mesenchymal Stem Cells Towards Osteoblastic Fate Through microRNA-21a-5p
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Bioengineering and Biotechnology"
DOI: 10.3389/fbioe.2021.801432
Abstract: The effective healing of a bone defect is dependent on the careful coordination of inflammatory and bone-forming cells. In the current work, pro-inflammatory M1 and anti-inflammatory M2 macrophages were co-cultured with primary murine bone mesenchymal… read more here.
Keywords: macrophage derived; bone; exosomes promote; mesenchymal stem ... See more keywords
M1 Microglia-derived Exosomes Promote Activation of Resting Microglia and Amplifies Proangiogenic Effects through Irf1/miR-155-5p/Socs1 Axis in the Retina
Sign Up to like & getrecommendations! Published in 2023 at "International Journal of Biological Sciences"
DOI: 10.7150/ijbs.79784
Abstract: Activation of microglia plays a key role in the development of neovascular retinal diseases. Therefore, it is essential to reveal its pathophysiological and molecular mechanisms to interfere with disease progression. Here a publicly available single-cell… read more here.
Keywords: mir 155; derived exosomes; microglia derived; exosomes promote ... See more keywords