Tracking Dye‐Independent Approach to Identify and Isolate In Vitro Expanded T Cells
Sign Up to like & getrecommendations! Published in 2019 at "Cytometry Part A"
DOI: 10.1002/cyto.a.23867
Abstract: T cell proliferation is routinely identified in vitro using tracking dyes or through detecting intracellular upregulation of the nuclear protein, Ki‐67. However, labeling with tracking dyes is cumbersome, associated with cellular toxicity, while Ki‐67 cannot… read more here.
Keywords: isolate vitro; tracking dye; cd71; identify isolate ... See more keywords
CRISPR Gene-Editing of Chemokine Receptors As a Novel Strategy to Redirect NK Cell Trafficking In Vivo
Sign Up to like & getrecommendations! Published in 2020 at "Blood"
DOI: 10.1182/blood-2020-141408
Abstract: Allogeneic and autologous natural killer (NK) cell-based therapies have proven to be safe in patients with hematological malignancies across multiple clinical trials. However, at present, only a small percentage of patients who have received NK… read more here.
Keywords: expression; ccr5; hematological malignancies; gene ... See more keywords
Single-cell transcriptomes and T cell receptors of vaccine-expanded apolipoprotein B-specific T cells
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Cardiovascular Medicine"
DOI: 10.3389/fcvm.2022.1076808
Abstract: Atherosclerotic cardiovascular diseases are the major cause of death worldwide. CD4 T cells responding to Apolipoprotein B (ApoB), the core protein of most lipoproteins, have been identified as critical disease modulators. In healthy individuals, ApoB-reactive… read more here.
Keywords: cell; apob; single cell; cell transcriptomes ... See more keywords
Using Expanded Natural Killer Cells as Therapy for Invasive Aspergillosis
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Fungi"
DOI: 10.3390/jof6040231
Abstract: Invasive aspergillosis (IA) is a major opportunistic fungal infection in patients with haematological malignancies. Morbidity and mortality rates are high despite anti-fungal treatment, as the compromised status of immune system prevents the host from responding… read more here.
Keywords: aspergillosis; treatment; expanded natural; using expanded ... See more keywords