Articles with "expanding organofluorine" as a keyword



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Expanding organofluorine chemical space: the design of chiral fluorinated isosteres enabled by I(i)/I(iii) catalysis

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Published in 2021 at "Chemical Science"

DOI: 10.1039/d1sc02880d

Abstract: Short aliphatic groups are prevalent in bioactive small molecules and play an essential role in regulating physicochemistry and molecular recognition phenomena. Delineating their biological origins and significance have resulted in landmark developments in synthetic organic… read more here.

Keywords: expanding organofluorine; iii catalysis; catalysis; chemical space ... See more keywords