Expanding the Substrate Scope of a Bacterial Nucleotidyltransferase via Allosteric Mutations.
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DOI: 10.1021/acsinfecdis.2c00402
Abstract: Bacterial glycoconjugates, such as cell surface polysaccharides and glycoproteins, play important roles in cellular interactions and survival. Enzymes called nucleotidyltransferases use sugar-1-phosphates and nucleoside triphosphates (NTPs) to produce nucleoside diphosphate sugars (NDP-sugars), which serve as… read more here.
Keywords: nucleotidyltransferase; expanding substrate; ndp sugars; scope bacterial ... See more keywords
Expanding Substrate Specificity of Salicylate Decarboxylase by Site-directed Mutagenesis for Expansion of the Entrance Region Connecting to the Substrate Access Tunnel
Sign Up to like & getrecommendations! Published in 2019 at "Chemistry Letters"
DOI: 10.1246/cl.180755
Abstract: Salicylate decarboxylase (Sdc, EC 4.1.1.91) from the yeast Trichosporon moniliiforme WU-0401 catalyzes the carboxylation of phenol to salicylic acid and is applicable to enzymatic Kolbe-Schmitt rea... read more here.
Keywords: expanding substrate; salicylate decarboxylase; decarboxylase; specificity salicylate ... See more keywords