Simultaneous evolutionary expansion and constraint of genomic heterogeneity in multifocal lung cancer
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DOI: 10.1038/s41467-017-00963-0
Abstract: Recent genomic analyses have revealed substantial tumor heterogeneity across various cancers. However, it remains unclear whether and how genomic heterogeneity is constrained during tumor evolution. Here, we sequence a unique cohort of multiple synchronous lung… read more here.
Keywords: genomic heterogeneity; heterogeneity; expansion constraint; constraint genomic ... See more keywords