Developments in Hematopoietic Stem Cell Expansion and Gene Editing Technologies.
Sign Up to like & getrecommendations! Published in 2018 at "Advances in experimental medicine and biology"
DOI: 10.1007/5584_2017_114
Abstract: Hematopoietic stem cells (HSCs) are rare cells, which housed in the adult bone marrow. They maintain all types of differentiated blood cells throughout life. Due to limited availability of HSCs for transplantation, treatment of various… read more here.
Keywords: gene editing; expansion; expansion gene; editing technologies ... See more keywords
Expansion of gene clusters, circular orders, and the shortest Hamiltonian path problem
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DOI: 10.1007/s00285-017-1197-3
Abstract: Clusters of paralogous genes such as the famous HOX cluster of developmental transcription factors tend to evolve by stepwise duplication of its members, often involving unequal crossing over. Gene conversion and possibly other mechanisms of… read more here.
Keywords: expansion gene; unequal crossing; shortest hamiltonian; gene clusters ... See more keywords
Expansion of the Gene Ontology knowledgebase and resources
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DOI: 10.1093/nar/gkw1108
Abstract: The Gene Ontology (GO) is a comprehensive resource of computable knowledge regarding the functions of genes and gene products. As such, it is extensively used by the biomedical research community for the analysis of -omics… read more here.
Keywords: ontology; expansion gene; knowledgebase; biology ... See more keywords