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Published in 2022 at "Wiley Interdisciplinary Reviews: RNA"
DOI: 10.1002/wrna.1732
Abstract: Expansion segments (ESs) are multinucleotide insertions present across phyla at specific conserved positions in eukaryotic rRNAs. ESs are generally absent in bacterial rRNAs with some exceptions, while the archaeal rRNAs have microexpansions at regions that…
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Keywords:
rrna expansion;
expansion segments;
story rrna;
finding functionality ... See more keywords
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Published in 2018 at "Molecular cell"
DOI: 10.1016/j.molcel.2018.11.023
Abstract: Expansion segments (ESs) are enigmatic insertions within the eukaryotic ribosome, the longest of which resemble tentacle-like extensions that vary in length and sequence across evolution, with a largely unknown function. By selectively engineering rRNA in…
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Keywords:
decoding function;
expansion segments;
segments ribosomes;
function ... See more keywords
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Published in 2024 at "Biochemical Society Transactions"
DOI: 10.1042/bst20231106
Abstract: Ribosomes are universally conserved cellular machines that catalyze protein biosynthesis. The active sites underly immense evolutionary conservation resulting in virtually identical core structures of ribosomes in all domains of life including organellar ribosomes. However, more…
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Keywords:
role;
biology;
rna expansion;
expansion segments ... See more keywords
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Published in 2020 at "Genome Biology and Evolution"
DOI: 10.1093/gbe/evaa170
Abstract: Abstract The ribosome’s common core, comprised of ribosomal RNA (rRNA) and universal ribosomal proteins, connects all life back to a common ancestor and serves as a window to relationships among organisms. The rRNA of the…
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Keywords:
common core;
ribosomal rna;
expansion segments;
supersized ribosomal ... See more keywords
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Published in 2024 at "Genome Biology and Evolution"
DOI: 10.1093/gbe/evae173
Abstract: Abstract Ribosomes are ribonucleoprotein complexes highly conserved across all domains of life. The size differences of ribosomal RNAs (rRNAs) can be mainly attributed to variable regions termed expansion segments (ESs) protruding out from the ribosomal…
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Keywords:
reduction ribosomal;
saprochaete clade;
species magnusiomyces;
expansion segments ... See more keywords
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Published in 2020 at "RNA"
DOI: 10.1261/rna.077123.120
Abstract: The large ribosomal RNAs of eukaryotes frequently contain expansion sequences that add to the size of the rRNAs but do not affect their overall structural layout and are compatible with major ribosomal function as an…
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Keywords:
bacterial archaeal;
ribosomal rnas;
expanded rrnas;
expansion ... See more keywords