Articles with "experimental adam17" as a keyword



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In Silico and Experimental ADAM17 Kinetic Modeling as Basis for Future Screening System for Modulators

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Published in 2022 at "International Journal of Molecular Sciences"

DOI: 10.3390/ijms23031368

Abstract: Understanding the mechanisms of modulators’ action on enzymes is crucial for optimizing and designing pharmaceutical substances. The acute inflammatory response, in particular, is regulated mainly by a disintegrin and metalloproteinase (ADAM) 17. ADAM17 processes several… read more here.

Keywords: adam17 kinetic; experimental adam17; modeling basis; kinetic modeling ... See more keywords