Combining molecular dynamics simulations and experimental analyses in protein misfolding.
Sign Up to like & getrecommendations! Published in 2019 at "Advances in protein chemistry and structural biology"
DOI: 10.1016/bs.apcsb.2019.10.001
Abstract: The fold of a protein determines its function and its misfolding can result in loss-of-function defects. In addition, for certain proteins their misfolding can lead to gain-of-function toxicities resulting in protein misfolding diseases such as… read more here.
Keywords: protein misfolding; molecular dynamics; experimental analyses; combining molecular ... See more keywords
Deformation and fracture of cylindrical tubes under detonation loading: A review of numerical and experimental analyses
Sign Up to like & getrecommendations! Published in 2019 at "International Journal of Pressure Vessels and Piping"
DOI: 10.1016/j.ijpvp.2019.05.003
Abstract: Abstract The dynamic load in tubes due to detonation has a number of applications, such as in oil pipeline systems and pulse detonation engines. Various experimental, analytical, and numerical investigations have been conducted to study… read more here.
Keywords: deformation fracture; numerical experimental; fracture; detonation ... See more keywords
Clinical implications of experimental analyses of AID function on predictive computational tools: Challenge of missense variants
Sign Up to like & getrecommendations! Published in 2020 at "Clinical Genetics"
DOI: 10.1111/cge.13737
Abstract: Due to the increased usage of high throughput sequencing for the diagnosis of genetically inherited disorders, it is vital to evaluate the risk of new variants and novel genes before accepting them in clinical practice.… read more here.
Keywords: overlapping variants; experimental analyses; clinical implications; implications experimental ... See more keywords
Numerical and Experimental Analyses of a Smart Fin Using Piezoelectric Actuator
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Aircraft"
DOI: 10.2514/1.c034739
Abstract: This paper introduces the comprehensive design of a thin piezoelectric-driven fin. Because of its hinge and flexible spar component having a low torsional stiffness with a thin composite actuator, the divergence speed is also predicted… read more here.
Keywords: smart fin; numerical experimental; fin; experimental analyses ... See more keywords
Bioinformatics and Experimental Analyses Reveal NFIC as an Upstream Transcriptional Regulator for Ischemic Cardiomyopathy
Sign Up to like & getrecommendations! Published in 2022 at "Genes"
DOI: 10.3390/genes13061051
Abstract: Ischemic cardiomyopathy (ICM) caused by coronary artery disease always leads to myocardial infarction and heart failure. Identification of novel transcriptional regulators in ICM is an effective method to establish new diagnostic and therapeutic strategies. In… read more here.
Keywords: bioinformatics experimental; ischemic cardiomyopathy; cardiomyopathy; analyses reveal ... See more keywords