Advances in experimental animal models of hepatocellular carcinoma.
Sign Up to like & getrecommendations! Published in 2023 at "Cancer medicine"
DOI: 10.1002/cam4.6163
Abstract: Hepatocellular carcinoma (HCC) is a common malignant tumor with insidious early symptoms, easy metastasis, postoperative recurrence, poor drug efficacy, and a high drug resistance rate when surgery is missed, leading to a low 5-year survival… read more here.
Keywords: hepatocellular carcinoma; animal models; experimental animal; models hepatocellular ... See more keywords
Translation from animal studies of novel pharmacological therapies to clinical trials in cardiac arrest: A systematic review.
Sign Up to like & getrecommendations! Published in 2020 at "Resuscitation"
DOI: 10.1016/j.resuscitation.2020.10.028
Abstract: BACKGROUND There is a lack of new promising therapies to improve the dismal outcomes from cardiac arrest. The objectives of this study were: (1) To identify novel pharmacological therapies investigated in experimental animal studies and… read more here.
Keywords: experimental animal; animal studies; novel pharmacological; cardiac arrest ... See more keywords
Experimental animal models for brain abscess: a systematic review.
Sign Up to like & getrecommendations! Published in 2022 at "British journal of neurosurgery"
DOI: 10.1080/02688697.2022.2160865
Abstract: BACKGROUND Brain abscess (BA) is a rare, but severe infection and experimental BA animal models may prove crucial for advances in treatment. This review describes the development of experimental BA models and the clinical advances… read more here.
Keywords: animal models; experimental animal; review; models brain ... See more keywords
Experimental animal models for rheumatoid arthritis
Sign Up to like & getrecommendations! Published in 2018 at "Immunopharmacology and Immunotoxicology"
DOI: 10.1080/08923973.2018.1434793
Abstract: Abstract Rheumatoid Arthritis (RA) is an autoimmune systemic disorder of unknown etiology and is characterized by chronic inflammation and synovial infiltration of immune cells. RA is associated with decreased life expectancy and quality of life.… read more here.
Keywords: induced arthritis; experimental animal; models rheumatoid; rheumatoid arthritis ... See more keywords
An experimental animal model of bronchopulmonary dysplasia: Secondary publication
Sign Up to like & getrecommendations! Published in 2021 at "Pediatrics International"
DOI: 10.1111/ped.14612
Abstract: Bronchopulmonary dysplasia (BPD) is a serious complication of preterm delivery and low birthweight infants. The incidence of BPD has not decreased, and there is no effective treatment for the disease. Since the survival rate of… read more here.
Keywords: bronchopulmonary dysplasia; experimental animal; animal model; animal models ... See more keywords
Neuroprotective Effect and Possible Mechanisms of Ginsenoside-Rd for Cerebral Ischemia/Reperfusion Damage in Experimental Animal: A Meta-Analysis and Systematic Review
Sign Up to like & getrecommendations! Published in 2022 at "Oxidative Medicine and Cellular Longevity"
DOI: 10.1155/2022/7650438
Abstract: Ischemic stroke, the most common type of stroke, can lead to a long-term disability with the limitation of effective therapeutic approaches. Ginsenoside-Rd (G-Rd) has been found as a neuroprotective agent. In order to investigate and… read more here.
Keywords: damage; experimental animal; reperfusion; analysis ... See more keywords
Experimental animal models and their use in understanding cysticercosis: A systematic review
Sign Up to like & getrecommendations! Published in 2022 at "PLoS ONE"
DOI: 10.1371/journal.pone.0271232
Abstract: Background Cysticercosis and Neurocysticercosis (NCC) can be studied using several animal species in experimental models which contributes to the understanding of the human form of the disease. Experimental infections of Taenia spp. are vital in… read more here.
Keywords: animal models; experimental animal; recovery rate; review ... See more keywords
Evaluation of Hepatoprotective and Gastroprotective Activities of Paspalidium flavidum Leaves Extract in Experimental Animal Models.
Sign Up to like & getrecommendations! Published in 2022 at "Cellular and molecular biology"
DOI: 10.14715/cmb/2022.68.10.2
Abstract: Paspalidium flavidum (watercrown grass), a medicinal plant, is traditionally used in liver ailments and stomach problems. The hepatoprotective and gastroprotective activities of the aqueous methanol extract of Paspalidium flavidum (AMEPF) were studied in experimental animal… read more here.
Keywords: experimental animal; hepatoprotective gastroprotective; paspalidium flavidum; amepf ... See more keywords
Experimental animal models for the study of moyamoya disease.
Sign Up to like & getrecommendations! Published in 2021 at "Neurosurgical focus"
DOI: 10.3171/2021.5.focus21282
Abstract: Moyamoya disease is a rare disorder of the cerebrovascular system affecting individuals in a bimodal age distribution and is characterized by progressive vascular stenosis of the bilateral supraclinoid internal carotid arteries with compensatory formation of… read more here.
Keywords: animal models; development; moyamoya disease; disease ... See more keywords
Experimental Animal Model Systems for Understanding Salivary Secretory Disorders
Sign Up to like & getrecommendations! Published in 2020 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms21228423
Abstract: Salivary secretory disorders are life-disrupting pathologic conditions with a high prevalence, especially in the geriatric population. Both patients and clinicians frequently feel helpless and get frustrated by the currently available therapeutic strategies, which consist mainly… read more here.
Keywords: experimental animal; model systems; animal model; secretory disorders ... See more keywords
Role of Nigella sativa and Its Constituent Thymoquinone on Chemotherapy-Induced Nephrotoxicity: Evidences from Experimental Animal Studies
Sign Up to like & getrecommendations! Published in 2017 at "Nutrients"
DOI: 10.3390/nu9060625
Abstract: Background: Most chemotherapeutic drugs are known to cause nephrotoxicity. Therefore, new strategies have been considered to prevent chemotherapy-induced nephrotoxicity. It is of note that Nigella sativa (NS), or its isolated compound Thymoquinone (TQ), has a… read more here.
Keywords: experimental animal; animal studies; induced nephrotoxicity; chemotherapy induced ... See more keywords