Type IV Collagen and SOX9 Are Molecular Targets of BET Inhibition in Experimental Glomerulosclerosis
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DOI: 10.3390/ijms24010486
Abstract: Progressive glomerulonephritis (GN) is characterized by an excessive accumulation of extracellular (ECM) proteins, mainly type IV collagen (COLIV), in the glomerulus leading to glomerulosclerosis. The current therapeutic approach to GN is suboptimal. Epigenetic drugs could… read more here.
Keywords: sox9; experimental glomerulosclerosis; type collagen; glomerulosclerosis ... See more keywords