Clinical and Experimental Human Sleep-Wake Pharmacogenetics.
Sign Up to like & getrecommendations! Published in 2018 at "Handbook of experimental pharmacology"
DOI: 10.1007/164_2018_175
Abstract: Sleep and wakefulness are highly complex processes that are elegantly orchestrated by fine-tuned neurochemical changes among neuronal and non-neuronal ensembles, nuclei, and networks of the brain. Important neurotransmitters and neuromodulators regulating the circadian and homeostatic… read more here.
Keywords: sleep wake; human sleep; wake disorders; wake pharmacogenetics ... See more keywords
Experimental Human Infection with Neisseria gonorrhoeae.
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DOI: 10.1007/978-1-4939-9496-0_25
Abstract: Experimental infection of male volunteers with Neisseria gonorrhoeae is safe and reproduces the clinical features of naturally acquired gonococcal urethritis. The human model is useful for testing the importance of putative gonococcal virulence factors for… read more here.
Keywords: human infection; infection neisseria; infection; neisseria gonorrhoeae ... See more keywords
Thrombospondin-1 Plays a Major Pathogenic Role in Experimental and Human Bronchopulmonary Dysplasia.
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DOI: 10.1164/rccm.202104-1021oc
Abstract: RATIONALE Extremely preterm infants develop bronchopulmonary dysplasia (BPD), a chronic lung injury that lacks effective treatment. Thrombospondin-1 is an anti-angiogenic protein that activates TGF-β1, a cytokine strongly linked to both experimental and human BPD. OBJECTIVES… read more here.
Keywords: lung; pathogenic role; thrombospondin; experimental human ... See more keywords
An Experimental Human Colonization Model with Pneumococcal Serotype 3 has the Potential to be Used for Vaccine Studies
Sign Up to like & getrecommendations! Published in 2022 at "American Journal of Respiratory and Critical Care Medicine"
DOI: 10.1164/rccm.202207-1342ed
Abstract: pollution and pediatric respiratory hospitalizations: effect modification by particle constituents and oxidative potential. Am J Respir Crit Care Med 2022;206:1370–1378. 13. WuY, Li S, Guo Y. Space-time-stratified case-crossover design in environmental epidemiology study.Health Data Science… read more here.
Keywords: pneumococcal serotype; colonization model; human colonization; experimental human ... See more keywords