Experimental models of maternal–fetal interface and their potential use for nanotechnology applications
Sign Up to like & getrecommendations! Published in 2019 at "Cell Biology International"
DOI: 10.1002/cbin.11222
Abstract: During pregnancy, the placenta regulates the transfer of oxygen, nutrients, and residual products between the maternal and fetal bloodstreams and is a key determinant of fetal exposure to xenobiotics from the mother. To study the… read more here.
Keywords: experimental models; interface potential; maternal fetal; nanotechnology ... See more keywords
The use of aliskiren as an antifibrotic drug in experimental models: A systematic review
Sign Up to like & getrecommendations! Published in 2019 at "Drug Development Research"
DOI: 10.1002/ddr.21610
Abstract: Aliskiren is an oral antihypertensive medication that acts by directly inhibiting renin. High levels of circulating renin and prorenin activate the pathological signaling pathway of fibrosis. This drug also reduces oxidative stress. Thus, the aim… read more here.
Keywords: experimental models; fibrosis; systematic review; drug ... See more keywords
Serotonergic mechanisms associated with experimental models of hypoxia: A systematic review
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Developmental Neuroscience"
DOI: 10.1002/jdn.10226
Abstract: The aim of this systematic review was to explore and discuss the literature concerning the effects of hypoxia or anoxia during the perinatal period on the serotoninergic network in rodents, through mechanisms that lead to… read more here.
Keywords: mechanisms associated; serotonergic mechanisms; review; systematic review ... See more keywords
Contribution of the diverse experimental models to unravelling the biological scope of dietary (poly)phenols
Sign Up to like & getrecommendations! Published in 2022 at "Journal of the Science of Food and Agriculture"
DOI: 10.1002/jsfa.11865
Abstract: Abstract The health benefits associated with (poly)phenols need to be supported by robust and insightful information on their biological effects. The use of in vitro, ex vivo, and in vivo models is crucial to demonstrate… read more here.
Keywords: information; contribution diverse; poly phenols; experimental models ... See more keywords
Multiple system atrophy: experimental models and reality
Sign Up to like & getrecommendations! Published in 2017 at "Acta Neuropathologica"
DOI: 10.1007/s00401-017-1772-0
Abstract: Multiple system atrophy (MSA) is a rapidly progressing fatal synucleinopathy of the aging population characterized by parkinsonism, dysautonomia, and in some cases ataxia. Unlike other synucleinopathies, in this disorder the synaptic protein, α-synuclein (α-syn), predominantly… read more here.
Keywords: atrophy experimental; experimental models; multiple system; system atrophy ... See more keywords
Cytokine Profile in Experimental Models of Critical Limb Ischemia in Rats
Sign Up to like & getrecommendations! Published in 2019 at "Bulletin of Experimental Biology and Medicine"
DOI: 10.1007/s10517-019-04666-y
Abstract: We studied the effect of intramuscular administration of a cellular product (mesenchymal stem cells, conditioned media, and erythropoietin) on cytokine levels in blood serum, conditioned media of bone marrow mononuclears, and calf muscles in Wistar… read more here.
Keywords: experimental models; profile experimental; cytokine profile; limb ischemia ... See more keywords
Photodynamic therapy using ultradeformable liposomes loaded with chlorine aluminum phthalocyanine against L. (V.) braziliensis experimental models.
Sign Up to like & getrecommendations! Published in 2018 at "Experimental parasitology"
DOI: 10.1016/j.exppara.2018.09.016
Abstract: Ultradeformable liposomes (UDLs) containing sodium cholate as edge activator could be an appropriate skin drug-delivery system for chloroaluminum phthalocyanine (ClAlPc) during photodynamic therapy (PDT) against cutaneous leishmaniasis (CL). The aim of this work was to… read more here.
Keywords: clalpc; photodynamic therapy; experimental models; braziliensis ... See more keywords
Experimental models of testicular development and function using human tissue and cells
Sign Up to like & getrecommendations! Published in 2018 at "Molecular and Cellular Endocrinology"
DOI: 10.1016/j.mce.2017.12.011
Abstract: The mammalian testis has two main roles, production of gametes for reproduction and synthesis of steroid- and peptide hormones for masculinization. These processes are tightly regulated and involve complex interactions between a number of germ… read more here.
Keywords: testis; experimental models; testicular development; function ... See more keywords
Experimental models in traumatic brain injury: from animal models to in vitro assays.
Sign Up to like & getrecommendations! Published in 2018 at "Medicina intensiva"
DOI: 10.1016/j.medin.2018.04.012
Abstract: Traumatic brain Injury (TBI) is a major public healthcare concern, affecting people of all ages. Despite advances in the diagnosis, monitoring and clinical management of TBI, many unresolved questions remain regarding its physiopathology. In an… read more here.
Keywords: brain injury; traumatic brain; experimental models; animal models ... See more keywords
Experimental models for ovarian cancer research.
Sign Up to like & getrecommendations! Published in 2022 at "Experimental cell research"
DOI: 10.1016/j.yexcr.2022.113150
Abstract: Among gynecological malignancies, ovarian cancer (OC) accounts for the highest mortality rate due to high therapeutic resistance, prolonged latency and a lack of effective treatments. This calls for preclinical models that could recapitulate the histological,… read more here.
Keywords: models ovarian; experimental models; ovarian cancer; research experimental ... See more keywords
Experimental models assessing bilirubin neurotoxicity
Sign Up to like & getrecommendations! Published in 2019 at "Pediatric Research"
DOI: 10.1038/s41390-019-0570-x
Abstract: The molecular and cellular events leading to bilirubin-induced neurotoxicity, the mechanisms regulating liver and intestine expression in neonates, and alternative pathways of bilirubin catabolism remain incompletely defined. To answer these questions, researchers have developed a… read more here.
Keywords: experimental models; assessing bilirubin; bilirubin neurotoxicity; neurotoxicity ... See more keywords