Dose-response assessment of chemically modified curcumin in experimental periodontitis.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of periodontology"
DOI: 10.1002/jper.18-0392
Abstract: BACKGROUND CMC2.24, a novel tri-ketonic chemically modified compound based on natural di-ketonic curcumin, has been shown to reduce bone loss and inflammatory mediators in experimental periodontitis, however, a potential dose-response relationship was not determined. The… read more here.
Keywords: production; experimental periodontitis; dose response; chemically modified ... See more keywords
Probiotic consumption can modify the resilience of periodontal tissues in rats under experimental periodontitis.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of periodontology"
DOI: 10.1002/jper.21-0555
Abstract: BACKGROUND This study evaluated the effects of systemic administration of Bifidobacterium animalis subsp. lactis HN019 (B. lactis HN019) on experimental periodontitis (EP) in rats. METHODS Thirty-two rats were allocated to groups C (control), C-HN019 (probiotic),… read more here.
Keywords: experimental periodontitis; group hn019; hn019; group ... See more keywords
Abaloparatide excels teriparatide in protecting against alveolar bone loss in experimental periodontitis.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of periodontology"
DOI: 10.1002/jper.22-0211
Abstract: BACKGROUND It was aimed to compare the effects of two osteoanabolic drugs, abaloparatide (ABL) and teriparatide (TPTD), on protecting alveolar bone in experimental periodontitis. METHODS Twenty-four 9-week-old male Sprague-Dawley rats were placed with silk ligature… read more here.
Keywords: experimental periodontitis; abl; alveolar bone; abl tptd ... See more keywords
D-Mannose alleviated alveolar bone loss in experimental periodontitis mice via regulating the anti-inflammatory effect of amino acids.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of periodontology"
DOI: 10.1002/jper.22-0294
Abstract: BACKGROUND Periodontitis is a chronic infectious disease caused by dysbiosis of oral microbiota, ultimately leading to periodontal alveolar bone loss. The oral subgingival microbiome, a key role in periodontitis pathogenesis, could alter the composition of… read more here.
Keywords: experimental periodontitis; bone loss; periodontitis; alveolar bone ... See more keywords
Physalis angulata reduces the progression of chronic experimental periodontitis by immunomodulatory mechanisms.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of ethnopharmacology"
DOI: 10.1016/j.jep.2021.113986
Abstract: ETHNOPHARMACOLOGICAL RELEVANCE Physalis angulata is an herb found in tropical and subtropical regions of the world; it is widely applied in popular medicine due to the therapeutic properties of the whole plant and its parts.… read more here.
Keywords: medicine; physalis angulata; chronic experimental; experimental periodontitis ... See more keywords
Experimental periodontitis in rats potentiates inflammation at a distant site: Role of B1 kinin receptor
Sign Up to like & getrecommendations! Published in 2018 at "Life Sciences"
DOI: 10.1016/j.lfs.2017.12.011
Abstract: &NA; It has been demonstrated that periodontitis, a chronic oral disease, can induce systemic inflammation which is associated with systemic diseases, including rheumatoid arthritis. Here, we evaluated whether periodontitis can modulate the inflammatory response at… read more here.
Keywords: inflammation; site; experimental periodontitis; periodontitis rats ... See more keywords
Peroxisome proliferator‐activated receptor &ggr; plays dual roles on experimental periodontitis in rats
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Clinical Periodontology"
DOI: 10.1111/jcpe.12891
Abstract: AIM To investigate the effects of peroxisome proliferator-activated receptor γ (PPARγ) on inflammation control and bone remodelling in experimental periodontitis in rats. MATERIALS AND METHODS Experimental periodontitis was induced in rats by thread ligation around… read more here.
Keywords: ppar; peroxisome proliferator; proliferator activated; bone ... See more keywords
Targeting therapeutic against C3b/C4b, SB002, on the inflammation-induced bone loss in experimental periodontitis.
Sign Up to like & getrecommendations! Published in 2023 at "Journal of clinical periodontology"
DOI: 10.1111/jcpe.13772
Abstract: AIMS To use experimental periodontitis models in rats to investigate the correlation between local expression of complement components C3b and C4b in periodontal tissues and disease severity, and to assess the therapeutic effects of targeting… read more here.
Keywords: experimental periodontitis; bone loss; periodontitis; c3b c4b ... See more keywords
Therapeutic potential for insulin on type 1 diabetes‐associated periodontitis: Analysis of experimental periodontitis in streptozotocin‐induced diabetic rats
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Diabetes Investigation"
DOI: 10.1111/jdi.13276
Abstract: The association between diabetes and periodontal disease is considered to be bidirectional. However, there is still controversy surrounding the relationship between periodontal disease and type 1 diabetes. We investigated whether insulin improves periodontitis without any… read more here.
Keywords: insulin; type diabetes; experimental periodontitis; therapeutic potential ... See more keywords
Impact of natural curcumin on the progression of experimental periodontitis in diabetic rats.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of periodontal research"
DOI: 10.1111/jre.12683
Abstract: OBJECTIVE To evaluate the role of natural curcumin (CURC) on experimental periodontitis (EP) in animals with diabetes mellitus (DM). MATERIAL AND METHODS One hundred rats were assigned to DM + placebo (PLA); DM + CURC; DM + insulin (INS); DM + CURC + INS; and… read more here.
Keywords: natural curcumin; curc; curc ins; experimental periodontitis ... See more keywords
Potential roles of miR-335-5p on pathogenesis of experimental periodontitis.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of periodontal research"
DOI: 10.1111/jre.12701
Abstract: BACKGROUND AND OBJECTIVE Periodontitis is a prevalent oral disease responsible for tooth loss. MicroRNAs have been proven crucial in bone disorders over the past decades. Promotive effect on osteogenic activities by microRNA-335-5p (miR-335-5p) has been… read more here.
Keywords: group; roles mir; bone; experimental periodontitis ... See more keywords