Examination of antimicrobial effect of fluoxetine in experimental sepsis model: An in vivo study
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Biochemical and Molecular Toxicology"
DOI: 10.1002/jbt.23240
Abstract: Since most infectious diseases can develop into sepsis, it is still a major medical problem. Some in‐vivo studies showed promising properties of fluoxetine in the treatment of infections. This study aims the antimicrobial effect of… read more here.
Keywords: sepsis; effect; fluoxetine; experimental sepsis ... See more keywords
Ivabradine Attenuates the Microcirculatory Derangements Evoked by Experimental Sepsis
Sign Up to like & getrecommendations! Published in 2017 at "Anesthesiology"
DOI: 10.1097/aln.0000000000001431
Abstract: Background: Experimental data suggest that ivabradine, an inhibitor of the pacemaker current in sinoatrial node, exerts beneficial effects on endothelial cell function, but it is unclear if this drug could prevent microcirculatory dysfunction in septic… read more here.
Keywords: sepsis; septic animals; derangements evoked; experimental sepsis ... See more keywords
Flagellin attenuates experimental sepsis in a macrophage-dependent manner
Sign Up to like & getrecommendations! Published in 2019 at "Critical Care"
DOI: 10.1186/s13054-019-2408-7
Abstract: BackgroundSepsis is the leading cause of death among critically ill patients, and no specific therapeutic agent is currently approved for the treatment of sepsis.MethodsWe assessed the effects of flagellin administration on survival, bacterial burden, and… read more here.
Keywords: sepsis; experimental sepsis; phagocytosis bacterial; dependent manner ... See more keywords
Inhibition of GPR 55 improves dysregulated immune response in experimental sepsis.
Sign Up to like & getrecommendations! Published in 2018 at "Clinical hemorheology and microcirculation"
DOI: 10.3233/ch-189320
Abstract: Sepsis is a medical condition caused by dysregulated systemic inflammatory response against infection, resulting in high mortality. Despite intensive research over the last few decades, the results from multiple clinical trials targeting specific inflammatory mediators… read more here.
Keywords: sepsis; response; experimental sepsis; inhibition ... See more keywords