Xanthohumol protects neuron from cerebral ischemia injury in experimental stroke
Sign Up to like & getrecommendations! Published in 2020 at "Molecular Biology Reports"
DOI: 10.1007/s11033-019-05128-4
Abstract: Treatment of antioxidants is necessary to protect ischemic stroke associated neuronal damage. Xanthohumol (XN), a natural flavonoid extracted from hops, has been reported to have potential function as an antioxidant and can be used for… read more here.
Keywords: ischemic stroke; protects neuron; experimental stroke; xanthohumol protects ... See more keywords
Neutrophil granulocytes promote flow stagnation due to dynamic capillary stalls following experimental stroke
Sign Up to like & getrecommendations! Published in 2021 at "Brain, Behavior, and Immunity"
DOI: 10.1016/j.bbi.2021.01.011
Abstract: Flow stagnation of peri-ischemic capillaries due to dynamic leukocyte stalls has been described to be a contributor to ongoing penumbral injury in transient brain ischemia, but has not been investigated in permanent experimental stroke so… read more here.
Keywords: capillary stalls; neutrophil granulocytes; experimental stroke; due dynamic ... See more keywords
Galectin-3 ablation does not affect infarct size or inflammatory cytokines after experimental stroke in 24-month-old female mice
Sign Up to like & getrecommendations! Published in 2022 at "Neuroreport"
DOI: 10.1097/wnr.0000000000001778
Abstract: Background The tissue damage following a focal stroke causes an inflammatory response that is thought to aggravate the disease state. Galectin-3 is a proinflammatory molecule that has been shown to play a significant role in… read more here.
Keywords: month old; experimental stroke; female mice; infarct size ... See more keywords
Dexpramipexole improves bioenergetics and outcome in experimental stroke
Sign Up to like & getrecommendations! Published in 2018 at "British Journal of Pharmacology"
DOI: 10.1111/bph.13790
Abstract: Dexpramipexole, a drug recently tested in patients with amyotrophic lateral sclerosis (ALS,) is able to bind F1Fo ATP synthase and increase mitochondrial ATP production. Here, we have investigated its effects on experimental ischaemic brain injury. read more here.
Keywords: outcome experimental; experimental stroke; pharmacology; dexpramipexole improves ... See more keywords
Regulatory B cells in experimental stroke
Sign Up to like & getrecommendations! Published in 2018 at "Immunology"
DOI: 10.1111/imm.12887
Abstract: Current treatment options for human stroke are limited mainly to the modestly effective infusion of tissue plasminogen activator (tPA), with additional improvement of functional independence and higher rates of angiographic revascularization observed after mechanical thrombectomy.… read more here.
Keywords: cells experimental; treatment; experimental stroke; regulatory cells ... See more keywords
Abstract TP117: Experimental Stroke Induces Chronic Gut Dysbiosis in Male C57BL/6J Mice
Sign Up to like & getrecommendations! Published in 2019 at "Stroke"
DOI: 10.1161/str.50.suppl_1.tp117
Abstract: Introduction: Recent literature implicates gut epithelia mucosa and intestinal microbiota as important players in post-stroke morbidity and mortality. As most studies have focused on the acute effe... read more here.
Keywords: stroke; induces chronic; abstract tp117; experimental stroke ... See more keywords
Experimental Stroke Differentially Affects Discrete Subpopulations of Splenic Macrophages
Sign Up to like & getrecommendations! Published in 2018 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2018.01108
Abstract: Changes to the immune system after stroke are complex and can result in both pro-inflammatory and immunosuppressive consequences. Following ischemic stroke, brain resident microglia are activated and circulating monocytes are recruited to the injury site.… read more here.
Keywords: differentially affects; affects discrete; stroke differentially; experimental stroke ... See more keywords