Articles with "experimental toolbox" as a keyword



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An Experimental Toolbox for Structure‐Based Hit Discovery for P. aeruginosa FabF, a Promising Target for Antibiotics

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Published in 2021 at "Chemmedchem"

DOI: 10.1002/cmdc.202100302

Abstract: FabF (3‐oxoacyl‐[acyl‐carrier‐protein] synthase 2), which catalyses the rate limiting condensation reaction in the fatty acid synthesis II pathway, is an attractive target for new antibiotics. Here, we focus on FabF from P. aeruginosa (PaFabF) as antibiotics against this… read more here.

Keywords: fabf; target; structure based; structure ... See more keywords