A revised model of TRAIL‐R2 DISC assembly explains how FLIP(L) can inhibit or promote apoptosis
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DOI: 10.15252/embr.201949254
Abstract: The long FLIP splice form FLIP(L) can act as both an inhibitor and promoter of caspase‐8 at death‐inducing signalling complexes (DISCs) formed by death receptors such as TRAIL‐R2 and related intracellular complexes such as the… read more here.
Keywords: trail disc; disc assembly; model; explains flip ... See more keywords