Ranpirnase Reduces HIV-1 Infection and Associated Inflammatory Changes in a Human Colorectal Explant Model.
Sign Up to like & getrecommendations! Published in 2018 at "AIDS research and human retroviruses"
DOI: 10.1089/aid.2017.0308
Abstract: Ranpirnase (RNP) is a low molecular weight type III endoribonuclease, which demonstrates broad antiviral and antitumor properties. We sought to characterize the antiviral activity of RNP against HIV-1 and to determine whether RNP modulates local… read more here.
Keywords: hiv infection; inflammatory changes; infection; explant model ... See more keywords
Enzymatic Drivers of Cartilage Breakdown: Insights From a Bovine Osteoarthritis Explant Model.
Sign Up to like & getrecommendations! Published in 2025 at "Orthopaedic surgery"
DOI: 10.1111/os.70202
Abstract: Osteoarthritis (OA) is a progressive joint disease characterized by cartilage degradation driven by matrix‐degrading enzymes. Reproducible ex vivo models are essential for studying early degenerative processes and evaluating potential therapeutics. However, there remains a lack… read more here.
Keywords: explant model; breakdown insights; enzymatic drivers; drivers cartilage ... See more keywords
Establishment of sheep nasal mucosa explant model and its application in antiviral research
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Microbiology"
DOI: 10.3389/fmicb.2023.1124936
Abstract: The nasal mucosa is the first barrier to pathogen invasion through the respiratory tract. Few studies have focused on nasal resistance to invasion by respiratory pathogens due to the lack of models related to the… read more here.
Keywords: sheep nasal; explant model; mucosa explant; model ... See more keywords