Articles with "exploitable metabolic" as a keyword



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Exploitable metabolic dependencies in MLL-ENL-induced leukemia.

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Published in 2020 at "Blood advances"

DOI: 10.1182/bloodadvances.2020001710

Abstract: Mixed-lineage leukemia (MLL) fusions are transcriptional activators that induce leukemia, with a dismal prognosis that mandates further elucidation of their transformation mechanism. In this study, knockdown of the direct MLL-ENL target gene polypyrimidine tract binding… read more here.

Keywords: mll enl; ser; ser gly; exploitable metabolic ... See more keywords