Articles with "exploiting altered" as a keyword



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Abstract IA26: Exploiting altered metabolism as a therapeutic strategy for RAS-driven cancers

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Published in 2023 at "Molecular Cancer Research"

DOI: 10.1158/1557-3125.ras23-ia26

Abstract: We recently determined that concurrent inhibition of autophagy, using the lysosomal inhibitor chloroquine (CQ), and of ERK, using a small molecule ERK inhibitor (ERKi), synergistically suppressed the growth of pancreatic ductal adenocarcinoma (PDAC) cell lines… read more here.

Keywords: inhibition; exploiting altered; therapeutic strategy; metabolism therapeutic ... See more keywords