Exploiting Natural Maltol for Synthesis of Novel Hydroxypyridone Derivatives as Promising Anti-Virulence Agents in Bactericides Discovery.
Sign Up to like & getrecommendations! Published in 2023 at "Journal of agricultural and food chemistry"
DOI: 10.1021/acs.jafc.3c00465
Abstract: Anti-infection strategies based on suppression of bacterial virulence factors represent a crucial direction for the development of new antibacterial agents to address the resistance triggered by traditional drugs'/pesticides' bactericidal activity. To identify and obtain more… read more here.
Keywords: maltol synthesis; natural maltol; virulence; virulence factors ... See more keywords
Exploiting natural riboswitches for aptamer engineering and validation
Sign Up to like & getrecommendations! Published in 2023 at "Nucleic Acids Research"
DOI: 10.1093/nar/gkac1218
Abstract: Abstract Over the past three decades, researchers have found that some engineered aptamers can be made to work well in test tubes but that these same aptamers might fail to function in cells. To help… read more here.
Keywords: aptamer engineering; engineering validation; natural riboswitches; guanine riboswitch ... See more keywords
Exploiting Natural Variation to Uncover an Alkene Biosynthetic Enzyme in Poplar[OPEN]
Sign Up to like & getrecommendations! Published in 2017 at "Plant Cell"
DOI: 10.1105/tpc.17.00338
Abstract: A ketoacyl CoA synthase (PotriKCS1) is key to the biosynthesis of alkenes in the cuticular waxes of poplar leaves. Alkenes are linear hydrocarbons with one or more double bonds. Despite their potential as biofuels and… read more here.
Keywords: alkene biosynthetic; natural variation; exploiting natural; uncover alkene ... See more keywords
Exploiting the Natural Properties of Extracellular Vesicles in Targeted Delivery towards Specific Cells and Tissues
Sign Up to like & getrecommendations! Published in 2020 at "Pharmaceutics"
DOI: 10.3390/pharmaceutics12111022
Abstract: Extracellular vesicles (EVs) are important mediators of intercellular communication that participate in many physiological/pathological processes. As such, EVs have unique properties related to their origin, which can be exploited for drug delivery applications in cell… read more here.
Keywords: extracellular vesicles; vesicles targeted; properties extracellular; delivery ... See more keywords