Exploiting the 4-Phenylquinazoline Scaffold for the Development of High Affinity Fluorescent Probes for the Translocator Protein (TSPO).
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DOI: 10.1021/acs.jmedchem.7b01031
Abstract: The quinazoline class was exploited to search for a new translocator protein (TSPO) fluorescent probe endowed with improved affinity and residence time (RT). Computational studies on an "in-house" collection of quinazoline derivatives, featuring highly steric… read more here.
Keywords: protein tspo; affinity; exploiting phenylquinazoline; fluorescent ... See more keywords