Exploiting the Thiobarbituric Acid Scaffold for Antibacterial Activity
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DOI: 10.1002/cmdc.201800414
Abstract: Thiobarbituric acid (TBA) has been considered a privileged structure for developing antimicrobial agents. Diversity was obtained at positions N and at C5 through acylation, Schiff base formation, Knoevenagel condensation, and thioamide and enamine formation. The… read more here.
Keywords: acid; thiobarbituric acid; acid scaffold; scaffold antibacterial ... See more keywords