Exploration of the structural requirements of Aurora Kinase B inhibitors by a combined QSAR, modelling and molecular simulation approach
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DOI: 10.1038/s41598-021-97368-3
Abstract: Aurora kinase B plays an important role in the cell cycle to orchestrate the mitotic process. The amplification and overexpression of this kinase have been implicated in several human malignancies. Therefore, Aurora kinase B is… read more here.
Keywords: structural requirements; kinase; exploration structural; aurora kinase ... See more keywords
Structurexplor: a platform for the exploration of structural features of RNA secondary structures
Sign Up to like & getrecommendations! Published in 2017 at "Bioinformatics"
DOI: 10.1093/bioinformatics/btx323
Abstract: Summary Discovering function-related structural features, such as the cloverleaf shape of transfer RNA secondary structures, is essential to understand RNA function. With this aim, we have developed a platform, named Structurexplor, to facilitate the exploration… read more here.
Keywords: rna secondary; secondary structures; structurexplor platform; structural features ... See more keywords