Using a Mathematical Modeling To Simulate Pharmacokinetics and Urinary Glucose Excretion of Luseogliflozin and Explore the Role of SGLT1/2 in Renal Glucose Reabsorption
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DOI: 10.1021/acsomega.2c06483
Abstract: (1) Purpose: To develop a mathematical model combining physiologically based pharmacokinetic and urinary glucose excretion (PBPK-UGE) to simultaneously predict pharmacokinetic (PK) and UGE changes of luseogliflozin (LUS) as well as to explore the role of… read more here.
Keywords: urinary glucose; reabsorption; glucose; explore role ... See more keywords
Quantitative Metabolomics to Explore the Role of Plasma Polyamines in Colorectal Cancer
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DOI: 10.3390/ijms24010101
Abstract: Colorectal cancer (CRC) is one of the major public health and socio-economic problems, which management demands the development of non-invasive screening tests. Assessment of circulating polyamines could be a valuable tool, although analytical problems still… read more here.
Keywords: role plasma; metabolomics explore; colorectal cancer; explore role ... See more keywords