Exploring biological efficacy of novel benzothiazole linked 2,5-disubstituted-1,3,4-oxadiazole hybrids as efficient α-amylase inhibitors: Synthesis, characterization, inhibition, molecular docking, molecular dynamics and Monte Carlo based QSAR studies.
Sign Up to like & getrecommendations! Published in 2021 at "Computers in biology and medicine"
DOI: 10.1016/j.compbiomed.2021.104876
Abstract: In an effort to explore a class of novel antidiabetic agents, we have made an effort to synergize the α-amylase inhibitory potential of 1,3-benzothiazole and 1,3,4-oxadiazole scaffolds by combining the two into a single structure… read more here.
Keywords: exploring biological; benzothiazole; inhibition; amylase ... See more keywords
Exploring biological efficacy of coumarin clubbed thiazolo[3,2-b][1,2,4]triazoles as efficient inhibitors of urease: A biochemical and in silico approach.
Sign Up to like & getrecommendations! Published in 2019 at "International journal of biological macromolecules"
DOI: 10.1016/j.ijbiomac.2019.09.105
Abstract: Combating several pathological conditions associated with ureolytic enzyme (urease) remains a formidable challenge because of the lack of effective and safe drug therapies. In this regard, the development of potent inhibitors of urease could be… read more here.
Keywords: exploring biological; inhibitors urease; biological efficacy; coumarin clubbed ... See more keywords
Exploring Biological Robustness for Reliable Multi-UAV Networks
Sign Up to like & getrecommendations! Published in 2021 at "IEEE Transactions on Network and Service Management"
DOI: 10.1109/tnsm.2021.3077544
Abstract: Unmanned Aerial Vehicles (UAVs), as aerial base stations, is a promising solution for providing end-to-end wireless communications to ground users, thanks to its positioning, flexibility, and autonomy. However, to provide end-to-end wireless communication services, all… read more here.
Keywords: exploring biological; network; reliable multi; biological robustness ... See more keywords
Exploring the Biological Activity and Mechanism of Xenoestrogens and Phytoestrogens in Cancers: Emerging Methods and Concepts
Sign Up to like & getrecommendations! Published in 2021 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms22168798
Abstract: Xenoestrogens and phytoestrogens are referred to as “foreign estrogens” that are produced outside of the human body and have been shown to exert estrogen-like activity. Xenoestrogens are synthetic industrial chemicals, whereas phytoestrogens are chemicals present… read more here.
Keywords: exploring biological; mechanism xenoestrogens; xenoestrogens phytoestrogens; phytoestrogens cancers ... See more keywords
Exploring the Biological Properties of Zn(II) Bisthiosemicarbazone Helicates
Sign Up to like & getrecommendations! Published in 2023 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms24032246
Abstract: The design of artificial helicoidal molecules derived from metal ions with biological properties is one of the objectives within metallosupramolecular chemistry. Herein, we report three zinc helicates derived from a family of bisthiosemicarbazone ligands with… read more here.
Keywords: properties bisthiosemicarbazone; chemistry; biological properties; bisthiosemicarbazone helicates ... See more keywords