Articles with "exploring flexibility" as a keyword



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Exploring the Flexibility of the Glycopeptide Antibiotic Crosslinking Cascade for Extended Peptide Backbones

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Published in 2022 at "ChemBioChem"

DOI: 10.1002/cbic.202200686

Abstract: The glycopeptide antibiotics (GPAs) are a clinically approved class of antimicrobial agents that classically function through the inhibition of bacterial cell‐wall biosynthesis by sequestration of the precursor lipid II. The oxidative crosslinking of the core peptide… read more here.

Keywords: biosynthesis; exploring flexibility; peptide; flexibility glycopeptide ... See more keywords